Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.57 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.55 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.46 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.46 |
| ▸ | TPH1 | P17752 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677411 | 0.87 | UGT2B7 (0.51) | FFAR1UGT2B7MMP9MEN1CYP1A2 | |
| SCHEMBL27989030 | 0.85 | TNF (0.56) | UGT2B7MMP9MEN1CYP1A2CYP2D6 | |
| SCHEMBL27980860 | 0.85 | TNF (0.56) | UGT2B7MMP9MEN1CYP1A2CYP2D6 | |
| SCHEMBL6172465 | 0.85 | TNF (0.56) | UGT2B7MMP9MEN1CYP1A2CYP2D6 | |
| SCHEMBL657936 | 0.82 | GABBR2 (0.50) | UGT2B7CYP2D6 | |
| SCHEMBL12320565 | 0.82 | SLC6A2 (0.54) | UGT2B7CYP2D6 | |
| SCHEMBL12278973 | 0.82 | UGT2B7 (0.50) | UGT2B7MMP9CYP2D6 | |
| SCHEMBL17451237 | 0.82 | UGT2B7 (0.50) | UGT2B7MMP9MEN1CYP1A2CYP2D6 | |
| SCHEMBL3967988 | 0.82 | ABCB11 (0.67) | FFAR1CYP1A2TSHR | |
| SCHEMBL5320805 | 0.81 | UGT2B7 (0.49) | UGT2B7MMP9MEN1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7982064-B2 | Method for preparing ortho-substituted aminoferrocenes | BROCK UNIVERSITY (CA) | 2011-07-19 | — | — | US | disclosed |
| US-20100137588-A1 | METHOD FOR PREPARING ORTHO-SUBSTITUTED AMINOFERROCENES | BROCK UNIVERSITY (CA) | 2010-06-03 | — | — | US | disclosed |
| US-4847413-A | Process for preparing 2-methyl-2-(methylsulfonyl) propionaldehyde O-(methylcarbamoyl) oxime as a water-wet cake | RHONE-POULENC NEDERLAND, B.V. (NL) | 1989-07-11 | — | — | US | disclosed |
| US-4097526-A | OXIDIZING SULFIDE COMPOUND WITH HYDROGEN PEROXIDE, A CARBOXYLIC ACID, MINERAL OR SULFONIC ACID CATALYSTS | UNION CARBIDE CORPORATION (US) | 1978-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100137588-A1 | METHOD FOR PREPARING ORTHO-SUBSTITUTED AMINOFERROCENES | LPO, AOC1, AOC2 | FFAR1 757/4885UGT2B7 2293/4885MMP9 4563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.