Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 7/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 7/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CDC42 | P60953 | 1/20 | 0.39 |
| ▸ | RAC1 | P63000 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1743242 | 1.00 | AKR1C3 (0.40) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL721604 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL721603 | 0.82 | AKR1C3 (0.48) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL1743289 | 0.77 | GSK3B (0.35) | PTGS2PPARG | |
| SCHEMBL10208268 | 0.72 | TDP1 (0.41) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL31355239 | 0.71 | MMP9 (0.45) | NPSR1LMNA | |
| SCHEMBL722003 | 0.71 | ALDH1A1 (0.48) | PPARGPPARAMAPT | |
| SCHEMBL1742554 | 0.66 | AKR1C3 (0.66) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL721608 | 0.65 | TDP1 (0.43) | AKR1C3AKR1C2PTGS2PTGS1TSHR | |
| SCHEMBL721609 | 0.65 | TDP1 (0.43) | AKR1C3AKR1C2PTGS2PTGS1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385951-A2 | PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | University College Cardiff Consultants, Ltd. (GB) | 2011-11-16 | — | — | EP | disclosed |
| US-20110254856-A1 | MOBILE TERMINAL AND METHOD OF CONTROLLING OPERATION OF THE MOBILE TERMINAL | LG ELECTRONICS INC. (KR) | 2011-10-20 | — | — | US | disclosed |
| WO-2010081082-A2 | PHOSPHORAMIDATE DERIVATIVES OF GUANOSINE NUCLEOSIDE COMPOUNDS FOR TREATMENT OF VIRAL INFECTIONS | UNIVERSITY COLLEGE OF CARDIFF CONSULTANTS LIMITED (GB) | 2010-07-15 | — | — | WO | disclosed |