SCHEMBL17451690

SCHEMBL17451690

c1ccc(N(c2ccccc2)c2ccc3c(c2)c2c4c5ccccc5n(-c5ccccc5)c4c4ccccc4c2n3-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
ATM Q13315 1/20 0.43
HSD17B10 Q99714 2/20 0.36
MAPK8 P45983 2/20 0.35
ALDH1A1 P00352 3/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
POLB P06746 1/20 0.33
TSHR P16473 1/20 0.33
BRCA1 P38398 1/20 0.33
GAA P10253 1/20 0.33
GFER P55789 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17123105 0.91 KDM4E (0.48) KDM4EL3MBTL1ATMHSD17B10MAPK8
SCHEMBL17451670 0.91 L3MBTL1 (0.40) KDM4EL3MBTL1ATMHSD17B10MAPK8
SCHEMBL15582828 0.89 KDM4E (0.46) KDM4EL3MBTL1ATMHSD17B10MAPK8
SCHEMBL18505026 0.88 KDM4E (0.50) KDM4EL3MBTL1ATMHSD17B10MAPK8
SCHEMBL14013709 0.88 KDM4E (0.40) KDM4EL3MBTL1ATMHSD17B10MAPK8
SCHEMBL15582829 0.87 KDM4E (0.44) KDM4EL3MBTL1ATMHSD17B10MAPK8
SCHEMBL19046783 0.87 KDM4E (0.41) KDM4EL3MBTL1ATM
SCHEMBL17123104 0.87 L3MBTL1 (0.44) KDM4EL3MBTL1ATMHSD17B10MAPK8
SCHEMBL16162885 0.87 KDM4E (0.47) KDM4EL3MBTL1ATMHSD17B10MAPK8
SCHEMBL17445381 0.87 L3MBTL1 (0.43) KDM4EL3MBTL1ATMHSD17B10MAPK8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9799835-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2017-10-24 US disclosed
US-9799835-B2 Compound for organic electric element, organic electric element comprising the same and electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2017-10-24 US disclosed
US-20160020410-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-21 US disclosed
US-20160020410-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2016-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160020410-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT COMPRISING THE SAME AND ELECTRONIC DEVICE THEREOF OR51E2, NFE2L2, ORAI2 KDM4E 458/4885L3MBTL1 1059/4885ATM 2254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.