SCHEMBL1745272

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1744798	0.91	FFAR1 (0.53)	FFAR4GFRA3RETFFAR1AKR1B1
	SCHEMBL1747354	0.91	FFAR4 (0.48)	FFAR4GFRA3RETFFAR1EPHX2
	SCHEMBL1744979	0.89	FFAR1 (0.54)	FFAR4GFRA3RETFFAR1AKR1B1
	SCHEMBL1746742	0.89	GFRA3 (0.45)	FFAR4GFRA3RETFFAR1AKR1B1
	SCHEMBL1745473	0.89	FFAR1 (0.48)	FFAR4GFRA3RETFFAR1AKR1B1
	SCHEMBL1746658	0.89	FFAR4 (0.46)	FFAR4GFRA3RETFFAR1PPARG
	SCHEMBL14567251	0.84	FFAR1 (0.50)	FFAR4GFRA3RETFFAR1AKR1B1
	SCHEMBL1745543	0.83	FFAR1 (0.51)	FFAR4GFRA3RETFFAR1AKR1B1
	SCHEMBL1746586	0.82	FFAR1 (0.46)	FFAR4FFAR1PPARGPPARA
	SCHEMBL1745475	0.82	FFAR1 (0.50)	FFAR4FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.