Dimpylate

Dimpylate

SCHEMBL17453

CCOP(=S)(OCC)Oc1cc(C)nc(C(C)C)n1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 1.00
TSHR P16473 4/20 1.00
CYP3A4 P08684 4/20 1.00
HSD17B10 Q99714 3/20 1.00
TP53 P04637 1/20 1.00
ACHE P22303 1/20 1.00
TDP1 Q9NUW8 5/20 0.60
MAPT P10636 4/20 0.42
MAPK1 P28482 2/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
ATM Q13315 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
KMT2A Q03164 2/20 0.39
KDM4E B2RXH2 3/20 0.38
POLB P06746 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.35
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA3 P07451 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimpylate SCHEMBL6118696 1.00 ALDH1A1 (1.00) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL27949432 0.99 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL28091934 0.99 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL6214077 0.99 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL3841005 0.99 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL1344740 0.99 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL6753267 0.99 ALDH1A1 (0.97) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL6891644 0.97 ALDH1A1 (0.94) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL4880297 0.97 ALDH1A1 (0.94) ALDH1A1TSHRCYP3A4HSD17B10TP53
Dimpylate SCHEMBL20770701 0.96 ALDH1A1 (0.92) ALDH1A1TSHRCYP3A4HSD17B10TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 226428 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12622925-B2 Edible enterosorbents used to mitigate acute exposures to ingestible environmental toxins following outbreaks, natural disasters and emergencies NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2026-05-12 US claimed
EP-4255391-B1 LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION METRIOPHARM AG (CH) 2026-05-06 EP claimed
EP-4734762-A1 BAIT COMPOSITIONS FMC Corporation (US) 2026-05-06 EP claimed
EP-4723893-A2 COMPOSITIONS AND METHODS TO MITIGATE PHYTOTOXIC EFFECTS OF AGRICHEMICALS Ascribe Bioscience Inc. (US) 2026-04-15 EP claimed
EP-4719059-A1 INCREASED PALATABILITY OF INSECTICIDAL INSECT BAITS Bio Logic Crop Science, S.L. (ES) 2026-04-08 EP claimed
US-20260083129-A1 PYRAZOLE AMIDE INSECTICIDES FMC CORP (US) 2026-03-26 US claimed
US-20260083130-A1 NOVEL SULFONATE BENZAMIDE COMPOUNDS FOR CONTROLLING INVERTEBRATE PESTS FMC CORP (US) 2026-03-26 US claimed
EP-4710766-A1 MIXTURES OF AMBRUTICIN WITH AT LEAST ONE FURTHER PESTICIDE BASF SE (DE) 2026-03-18 EP claimed
US-20260068882-A1 ARTHROPOD CONTROLLING COMPOSITION FIRMENICH & CIE (CH) 2026-03-12 US claimed
US-12568969-B2 Pyridine compounds for controlling invertebrate pests FMC CORPORATION (US) 2026-03-10 US claimed
US-4116828-A ADSORPTION WITH CLAY INTERNATIONAL TELEPHONE AND TELEGRAPH CORP. (US) 1978-09-26 US claimed
US-4093461-A ORTHOQUINONE OR NAPHTHOQUINONE DIAZIDE AND CONDENSATION PRODUCT OF AROMATIC DIANHYDRIDE AND AROMATIC DI-PRIMARY AMINE GAF CORPORATION (US) 1978-06-06 US claimed
US-4059449-A NOVOLAK, NAPHTHOQUINONE-(1,2)-DIAZIDE SULFONATE RCA CORPORATION (US) 1977-11-22 US claimed
US-4036644-A Photoresist process and photosensitive O-quinone diazide article with aliphatic carboxylic acid as adhesion promotor INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1977-07-19 US claimed
US-4025164-A Liquid crystal display device for colored display of information with a selective polarizer BBC BROWN BOVERI & COMPANY LIMITED (CH) 1977-05-24 US claimed
US-4020176-A Highly fluorinated diazides and process therefor POLAROID CORPORATION (US) 1977-04-26 US claimed
US-4016265-A Synergistic insecticidal compositions containing β-exotoxin SANDOZ, INC. (US) 1977-04-05 US claimed
US-3974481-A Machine for the finding of an optimum passage SOCIETE CYBCO (FR) 1976-08-10 US claimed
US-3960320-A Combustion optimizer FORNEY ENGINEERING COMPANY (US) 1976-06-01 US claimed
US-3948667-A HOMO- AND CO-POLYMERS OF CYCLIZED BUTADIENE AND A CROSSLINKING AGENT JAPAN SYNTHETIC RUBBER COMPANY LIMITED (JA) 1976-04-06 US claimed