Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.97 |
| ▸ | TSHR | P16473 | 4/20 | 0.97 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.97 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.97 |
| ▸ | TP53 | P04637 | 1/20 | 0.97 |
| ▸ | ACHE | P22303 | 1/20 | 0.97 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dimpylate SCHEMBL17453 | 0.99 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL6118696 | 0.99 | ALDH1A1 (1.00) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL28091934 | 0.97 | ALDH1A1 (0.97) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL27949432 | 0.97 | ALDH1A1 (0.97) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL6214077 | 0.97 | ALDH1A1 (0.97) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL1344740 | 0.97 | ALDH1A1 (0.97) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL6753267 | 0.97 | ALDH1A1 (0.97) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL6891644 | 0.96 | ALDH1A1 (0.94) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL4880297 | 0.96 | ALDH1A1 (0.94) | ALDH1A1TSHRCYP3A4HSD17B10TP53 | |
| Dimpylate SCHEMBL20770701 | 0.94 | ALDH1A1 (0.92) | ALDH1A1TSHRCYP3A4HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114901348-A | Augmenting VO in heart failure patients using cardiocontractile regulatory stimulation 2 Peak value | 脉冲动力公司 | 2022-08-12 | — | — | CN | disclosed |
| EP-3069284-B1 | COMPUTER-ASSISTED MODELING FOR TREATMENT DESIGN | HINGE THERAPEUTICS INC (US) | 2020-06-10 | — | — | EP | disclosed |
| US-20180261331-A1 | COMPUTER-ASSISTED MODELING FOR TREATMENT DESIGN | InfiniteBio | 2018-09-13 | — | — | US | disclosed |
| EP-3069284-A1 | COMPUTER-ASSISTED MODELING FOR TREATMENT DESIGN | Infinitebio (US) | 2016-09-21 | — | — | EP | disclosed |
| US-20150142408-A1 | COMPUTER-ASSISTED MODELING FOR TREATMENT DESIGN | HINGE THERAPEUTICS, INC. | 2015-05-21 | — | — | US | disclosed |
| US-20150003595-A1 | System, Method and Computer Program Product for a Universal Call Capture Device | TRANSPARENCY SCIENCES LLC (US) | 2015-01-01 | — | — | US | disclosed |
| US-20130110565-A1 | System, Method and Computer Program Product for Distributed User Activity Management | TRANSPARENCY SCIENCES, LLC (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2012148934-A1 | SYSTEM, METHOD AND COMPUTER PROGRAM PRODUCT FOR DISTRIBUTED USER ACTIVITY MANAGEMENT | TRANSPARENCY SCIENCES, LLC (US) | 2012-11-01 | — | — | WO | disclosed |
| WO-2009035751-A1 | DISTRIBUTED TRAIN CONTROL | GENERAL ELECTRIC COMPANY (US) | 2009-03-19 | — | — | WO | disclosed |
| US-7395141-B1 | Distributed train control | GENERAL ELECTRIC COMPANY (US) | 2008-07-01 | — | — | US | disclosed |