SCHEMBL1745362

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1746563	0.94	KMT2A (0.49)	NPSR1FFAR1FFAR4KMT2AMEN1
	SCHEMBL1746853	0.93	FFAR1 (0.57)	FFAR1FFAR4AKR1B1
	SCHEMBL3911602	0.90	NPSR1 (0.51)	NPSR1FFAR1FFAR4AKR1B1KMT2A
	SCHEMBL1744670	0.85	FFAR1 (0.57)	NPSR1FFAR1FFAR4AKR1B1KMT2A
	SCHEMBL3917024	0.85	NPSR1 (0.53)	NPSR1FFAR1FFAR4KMT2AMEN1
	SCHEMBL1746617	0.85	KMT2A (0.50)	NPSR1FFAR1FFAR4KMT2AMEN1
	SCHEMBL4029428	0.84	KMT2A (0.51)	NPSR1KMT2AMEN1MAPTL3MBTL1
	SCHEMBL1745444	0.83	KMT2A (0.48)	NPSR1FFAR1KMT2AMEN1MAPT
	SCHEMBL1747402	0.82	FFAR1 (0.48)	NPSR1FFAR1FFAR4KMT2AMEN1
	SCHEMBL3918017	0.82	FFAR1 (0.57)	FFAR1FFAR4AKR1B1PPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.