Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.68 |
| ▸ | FAAH | O00519 | 5/20 | 0.63 |
| ▸ | MGLL | Q99685 | 4/20 | 0.63 |
| ▸ | BCHE | P06276 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15897789 | 0.88 | BCHE (0.74) | MAPTFAAHMGLLBCHETP53 | |
| SCHEMBL17452431 | 0.82 | MAPT (0.58) | MAPTFAAHMGLLBCHESMN1; SMN2 | |
| SCHEMBL17452422 | 0.81 | GAA (0.57) | MAPTBCHESMN1; SMN2POLBRAB9A | |
| SCHEMBL27178213 | 0.80 | SMN1; SMN2 (0.74) | MAPTSMN1; SMN2POLBRAB9AL3MBTL1 | |
| SCHEMBL27178325 | 0.80 | SMN1; SMN2 (0.74) | MAPTSMN1; SMN2POLBRAB9AL3MBTL1 | |
| SCHEMBL27178327 | 0.80 | SMN1; SMN2 (0.74) | MAPTSMN1; SMN2POLBRAB9AL3MBTL1 | |
| SCHEMBL27178219 | 0.80 | SMN1; SMN2 (0.74) | MAPTSMN1; SMN2POLBRAB9AL3MBTL1 | |
| SCHEMBL13941421 | 0.78 | PLK4 (0.52) | MAPTFAAHMGLLBCHERAB9A | |
| SCHEMBL15849842 | 0.78 | MAPT (0.56) | MAPTFAAHMGLLSMN1; SMN2POLB | |
| SCHEMBL28874997 | 0.77 | MEN1 (0.57) | MAPTSMN1; SMN2POLBRAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10730848-B2 | Protective molecules against anthrax toxin | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2020-08-04 | — | — | US | disclosed |
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-01-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160016930-A1 | PROTECTIVE MOLECULES AGAINST ANTHRAX TOXIN | ANTXR2, TSG101, ANXA1 | MAPT 4617/4885FAAH 1215/4885MGLL 2351/4885 |
| US-10730848-B2 | Protective molecules against anthrax toxin | ANTXR2, TSG101, ANXA1 | MAPT 4617/4885FAAH 1215/4885MGLL 2351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.