Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 9/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.57 |
| ▸ | GAA | P10253 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 9/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CASP6 | P55212 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15187708 | 0.93 | RAB9A (0.57) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL15177203 | 0.90 | ALDH1A1 (0.54) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL4413307 | 0.88 | GAA (0.69) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL13345208 | 0.88 | GAA (0.69) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL3273659 | 0.88 | GAA (0.69) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL11325422 | 0.85 | MEN1 (0.61) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL12670669 | 0.84 | MAPT (0.67) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL23392561 | 0.84 | MEN1 (0.64) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL6285948 | 0.84 | RAB9A (0.66) | MEN1KMT2AGAARAB9AMAPT | |
| SCHEMBL6285944 | 0.84 | RAB9A (0.66) | MEN1KMT2AGAARAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260104-B | Preparation method of fullerene tetrahydropyridazine compound | 合肥学院 | 2023-10-27 | — | — | CN | claimed |
| CN-115260104-A | Preparation method of fullerene tetrahydropyridazine compound | 合肥学院 | 2022-11-01 | — | — | CN | claimed |
| CN-115260104-B | Preparation method of fullerene tetrahydropyridazine compound | 合肥学院 | 2023-10-27 | — | — | CN | disclosed |
| CN-115260104-A | Preparation method of fullerene tetrahydropyridazine compound | 合肥学院 | 2022-11-01 | — | — | CN | disclosed |