SCHEMBL1745440

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1747100	0.93	FFAR1 (0.45)	GFRA3RETHCAR2FFAR1HRH3
	SCHEMBL1747068	0.92	FFAR1 (0.43)	GFRA3RETHCAR2FFAR1HRH3
	SCHEMBL1744691	0.91	HRH3 (0.42)	GFRA3RETHCAR2FFAR1HRH3
	SCHEMBL1746658	0.91	FFAR4 (0.46)	GFRA3RETHCAR2FFAR1HRH3
	SCHEMBL1744798	0.89	FFAR1 (0.53)	GFRA3RETFFAR1AKR1B1FFAR4
	SCHEMBL1744736	0.88	FFAR1 (0.44)	GFRA3RETFFAR1FFAR4PPARD
	SCHEMBL1747248	0.86	GRIN2B (0.44)	FFAR1PPARD
	SCHEMBL1744689	0.86	FFAR1 (0.46)	GFRA3RETFFAR1PPARD
	SCHEMBL1744612	0.86	FFAR1 (0.48)	FFAR1FFAR4
	SCHEMBL1744692	0.86	FFAR1 (0.52)	GFRA3FFAR1HRH3GFRA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.