Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.92 |
| ▸ | RORB | Q92753 | 2/20 | 0.83 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175507 | 0.96 | RORC (1.00) | RORCRORBNR1I2 | |
| SCHEMBL174641 | 0.95 | RORC (1.00) | RORCRORBNR1I2 | |
| SCHEMBL175457 | 0.95 | RORC (0.89) | RORCRORBNR1I2 | |
| SCHEMBL175183 | 0.91 | RORC (1.00) | RORCRORB | |
| SCHEMBL175486 | 0.90 | RORC (0.93) | RORCRORBNR1I2 | |
| SCHEMBL175371 | 0.90 | RORC (1.00) | RORCRORBNR1I2 | |
| SCHEMBL174114 | 0.90 | RORC (1.00) | RORCRORBNR1I2 | |
| SCHEMBL174154 | 0.90 | RORC (0.85) | RORCRORBNR1I2 | |
| SCHEMBL175040 | 0.90 | RORC (1.00) | RORCRORBNR1I2 | |
| SCHEMBL175493 | 0.88 | RORC (1.00) | RORCRORBNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |
| WO-2012027965-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2012-03-08 | — | — | WO | disclosed |