Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.50 |
| ▸ | DPP7 | Q9UHL4 | 12/20 | 0.50 |
| ▸ | DPP8 | Q6V1X1 | 10/20 | 0.50 |
| ▸ | DPP9 | Q86TI2 | 9/20 | 0.50 |
| ▸ | FAP | Q12884 | 5/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172842 | 0.83 | DPP4 (0.56) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL542217 | 0.83 | DPP4 (0.61) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL7406032 | 0.82 | DPP4 (0.62) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL7029434 | 0.82 | DPP4 (0.62) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL11280094 | 0.81 | ACE (0.61) | DPP4 | |
| SCHEMBL11280092 | 0.81 | ACE (0.61) | DPP4 | |
| SCHEMBL145916 | 0.81 | DPP4 (0.63) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL27920297 | 0.81 | DPP4 (0.53) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL8852004 | 0.80 | DPP7 (0.78) | DPP4DPP7DPP8DPP9FAP | |
| SCHEMBL2182868 | 0.80 | DPP7 (0.78) | DPP4DPP7DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2019-03-07 | — | — | US | disclosed |
| US-9682153-B2 | Polymer conjugates of therapeutic peptides | NEKTAR THERAPEUTICS (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | DPP4 525/4885DPP7 450/4885DPP8 644/4885 |
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | DPP4 525/4885DPP7 450/4885DPP8 644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.