SCHEMBL542217

SCHEMBL542217

N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1[C]=O

nearest known ligand 0.61

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DPP4 P27487 18/20 0.61
▸ DPP8 Q6V1X1 13/20 0.49
▸ DPP7 Q9UHL4 10/20 0.49
▸ DPP9 Q86TI2 6/20 0.49
▸ FAP Q12884 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL145916 0.85 DPP4 (0.63) DPP4DPP8DPP7DPP9FAP
SCHEMBL7029434 0.84 DPP4 (0.62) DPP4DPP8DPP7DPP9FAP
SCHEMBL7406032 0.84 DPP4 (0.62) DPP4DPP8DPP7DPP9FAP
SCHEMBL17456229 0.83 DPP4 (0.50) DPP4DPP8DPP7DPP9FAP
SCHEMBL7172842 0.82 DPP4 (0.56) DPP4DPP8DPP7DPP9FAP
SCHEMBL3083059 0.81 DPP4 (0.47) DPP4DPP8DPP7DPP9
SCHEMBL27920297 0.79 DPP4 (0.53) DPP4DPP8DPP7DPP9FAP
SCHEMBL8852004 0.78 DPP7 (0.78) DPP4DPP8DPP7DPP9FAP
SCHEMBL2182868 0.78 DPP7 (0.78) DPP4DPP8DPP7DPP9FAP
SCHEMBL4956097 0.78 DPP7 (0.78) DPP4DPP8DPP7DPP9FAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2545384-A1 METHOD FOR DETERMINING THE CONCENTRATION OF A PEPTIDE JPT Peptide Technologies GmbH (DE) 2013-01-16 — — EP claimed
WO-2011110341-A1 METHOD FOR DETERMINING THE CONCENTRATION OF A PEPTIDE JPT PEPTIDE TECHNOLOGIES GMBH (DE) 2011-09-15 — — WO claimed
EP-3806888-B1 PDE5 DERIVED REGULATORY CONSTRUCTS AND METHODS OF USE IN IMMUNOTHERAPY OBSIDIAN THERAPEUTICS INC (US) 2024-01-31 — — EP disclosed
CN-110831961-B CD19 compositions and methods for immunotherapy 黑曜石疗法公司 2024-01-02 — — CN disclosed
US-11666642-B2 PDE5 compositions and methods for immunotherapy OBSIDIAN THERAPEUTICS, INC. (US) 2023-06-06 — — US disclosed
US-11629340-B2 DHFR tunable protein regulation OBSIDIAN THERAPEUTICS, INC. (US) 2023-04-18 — — US disclosed
US-20230092895-A1 TANDEM CD19 CAR-BASED COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY OBSIDIAN THERAPEUTICS, INC. 2023-03-23 — — US disclosed
US-20230074330-A1 PDE5 COMPOSITIONS AND METHODS FOR IMMUNOTHERAPY OBSIDIAN THERAPEUTICS, INC. (US) 2023-03-09 — — US disclosed
US-20220403001-A1 PDE5 DERIVED REGULATORY CONSTRUCTS AND METHODS OF USE IN IMMUNOTHERAPY OBSIDIAN THERAPEUTICS, INC. (US) 2022-12-22 — — US disclosed
US-20220213449-A1 DHFR TUNABLE PROTEIN REGULATION OBSIDIAN THERAPEUTICS, INC. (US) 2022-07-07 — — US disclosed
US-20220056092-A1 MEMBRANE BOUND IL12 COMPOSITIONS AND METHODS FOR TUNABLE REGULATION OBSIDIAN THERAPEUTICS, INC. (US) 2022-02-24 — — US disclosed
WO-2001036608-A1 REVERSIBLY INACTIVATED ACIDIFIED PLASMIN BAYER CORPORATION (US) 2001-05-25 — — WO disclosed
WO-2000055322-A1 IMPROVED METHODS FOR RECOMBINANT PEPTIDE PRODUCTION XOMA TECHNOLOGY LTD. (US) 2000-09-21 — — WO disclosed
EP-0904370-A1 METHODS FOR RECOMBINANT MICROBIAL PRODUCTION OF BPI-FUSION PROTEINS AND BPI-DERIVED PEPTIDES Xoma Corporation (US) 1999-03-31 — — EP disclosed
EP-0885899-A1 Method for obtaining peptide fragments by use of fluorinated organic acids SEIKO INSTRUMENTS INC. (JP) 1998-12-23 — — EP disclosed
US-5851802-A Methods for recombinant microbial production of fusion proteins and BPI-derived peptides XOMA CORPORATION (US) 1998-12-22 — — US disclosed
WO-1997035009-A1 METHODS FOR RECOMBINANT MICROBIAL PRODUCTION OF BPI-FUSION PROTEINS AND BPI-DERIVED PEPTIDES XOMA CORPORATION (US) 1997-09-25 — — WO disclosed
US-5464756-A EFFICIENCY GENENTECH (US) 1995-11-07 — — US disclosed
US-5459061-A Hybridomas producing monoclonal antibodies which specifically bind to continuous epitope on the human EGF receptor and compete with EGF for binding to the EGF receptor W. ALTON JONES CELL SCIENCE CENTER, INC. (US) 1995-10-17 — — US disclosed
EP-0470976-B1 PROCESSES AND COMPOSITIONS FOR THE ISOLATION OF HUMAN RELAXIN GENENTECH, INC. (US) 1993-03-31 — — EP disclosed
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