Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | IDE | P14735 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17457552 | 1.00 | HDAC1 (0.56) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL17472004 | 0.87 | HDAC1 (0.71) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL20767993 | 0.87 | HDAC1 (0.71) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL17457541 | 0.81 | HDAC1 (0.75) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL17457542 | 0.81 | HDAC1 (0.75) | HDAC1HDAC3HDAC2MAPK1NCOR2 | |
| SCHEMBL6692602 | 0.79 | TRPA1 (0.67) | HDAC1MAPK1TRPA1IDENPC1 | |
| SCHEMBL30863757 | 0.79 | TRPA1 (0.67) | HDAC1MAPK1TRPA1IDENPC1 | |
| SCHEMBL6692597 | 0.79 | TRPA1 (0.67) | HDAC1MAPK1TRPA1IDENPC1 | |
| SCHEMBL30827268 | 0.78 | IDE (0.75) | MAPK1TRPA1IDENPC1RAB9A | |
| SCHEMBL28907337 | 0.78 | IDE (0.75) | MAPK1TRPA1IDENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160022817-A1 | Photoswitchable HDAC Inhibitors | THE GENERAL HOSPITAL CORPORATION (US) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022817-A1 | Photoswitchable HDAC Inhibitors | HDAC1, HDAC4, HDAC3 | HDAC1 1/4885HDAC3 3/4885HDAC2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.