Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Acid SCHEMBL28784194 | 0.96 | ALOX15 (0.49) | PTPN1ALOX15KDM4EMEN1KMT2A | |
| Terephthalic Acid SCHEMBL6654997 | 0.94 | CYP2C19 (0.44) | PTPN1ALOX15KDM4EMEN1KMT2A | |
| Terephthalic Acid SCHEMBL17685563 | 0.93 | ALOX15 (0.52) | PTPN1ALOX15KDM4ECA1CA2 | |
| Terephthalic Acid SCHEMBL7867064 | 0.91 | ALOX15 (0.50) | PTPN1ALOX15KDM4ECA1CA2 | |
| Terephthalic Acid SCHEMBL20545564 | 0.91 | ALOX15 (0.50) | PTPN1ALOX15KDM4ECA1CA2 | |
| SCHEMBL27738428 | 0.88 | HSD17B10 (0.54) | PTPN1ALOX15KDM4ECA1CA2 | |
| Terephthalic Acid SCHEMBL8092861 | 0.86 | ALOX15 (0.46) | PTPN1ALOX15KDM4EMEN1KMT2A | |
| Isophthalic Acid SCHEMBL17457903 | 0.86 | HDAC3 (0.42) | PTPN1ALOX15CA1CA2CA9 | |
| Benzene SCHEMBL10638262 | 0.85 | ALOX15 (0.59) | ALOX15KDM4ECA1CA2CA9 | |
| SCHEMBL65889 | 0.85 | ALOX15 (0.59) | ALOX15KDM4ECA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105103303-B | Back sheet for solar cell and solar cell module | 富士胶片株式会社 | 2017-04-05 | — | — | CN | disclosed |
| US-20160071992-A1 | BACK SHEET FOR SOLAR CELLS AND SOLAR CELL MODULE | FUJIFILM CORPORATION (JP) | 2016-03-10 | — | — | US | disclosed |
| US-20160027941-A1 | MULTILAYER FILM, BACK SHEET FOR SOLAR CELL MODULE, AND SOLAR CELL MODULE | FUJIFILM CORPORATION (JP) | 2016-01-28 | — | — | US | disclosed |
| CN-105103303-A | Back sheet for solar cell and solar cell module | FUJIFILM CORP | 2015-11-25 | — | — | CN | disclosed |
| CN-105102228-A | Laminated film, back sheet for solar cell module, and solar cell module | FUJIFILM CORP | 2015-11-25 | — | — | CN | disclosed |