SCHEMBL17457909

SCHEMBL17457909

CC(O)C(CC(N)=O)C(N)=O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 4/20 0.40
ALDH1A1 P00352 2/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
PDCD1LG2 Q9BQ51 1/20 0.30
CD274 Q9NZQ7 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21557495 0.82 ECE1 (0.50) ECE1ALDH1A1TDP1
SCHEMBL7426948 0.81 ECE1 (0.42) ECE1ALDH1A1MAPT
SCHEMBL2680479 0.81 ECE1 (0.38) ECE1ALDH1A1TDP1
SCHEMBL27960336 0.80 ECE1 (0.40) ECE1ALDH1A1TDP1
SCHEMBL27709415 0.79 ECE1 (0.34) ECE1ALDH1A1TDP1
SCHEMBL8048401 0.77
SCHEMBL8046665 0.77
SCHEMBL9796962 0.76 CA1 (0.34) ECE1
SCHEMBL3504203 0.76 ECE1 (0.38) ECE1ALDH1A1
SCHEMBL6938151 0.75 FOLH1 (0.37) ECE1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116710505-A Functionalized poly (glycine) -poly (alkylene imine) copolymers, their preparation and their use for preparing formulations of anionic active ingredients and effect substances or for complexing anionic active ingredients and effect substances 耶拿弗里德里希·席勒大学 2023-09-05 CN disclosed
CN-116601209-A Functionalized poly (glycine) -poly (alkylene imine) copolymers, their preparation and use for preparing formulations of active ingredients and formulations of special effect substances 耶拿弗里德里希·席勒大学 2023-08-15 CN disclosed
US-10106514-B2 Thermoresponsive polyesters THE UNIVERSITY OF AKRON (US) 2018-10-23 US disclosed
US-20160024251-A1 THERMORESPONSIVE POLYESTERS THE UNIVERSITY OF AKRON 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10106514-B2 Thermoresponsive polyesters COASY, CD14, NCAPH ECE1 1364/4885ALDH1A1 1850/4885MAPT 350/4885
US-20160024251-A1 THERMORESPONSIVE POLYESTERS COASY, CD14, NCAPH ECE1 1364/4885ALDH1A1 1850/4885MAPT 350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.