Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11901924 | 0.85 | L3MBTL1 (0.41) | — | |
| SCHEMBL18662041 | 0.81 | CYP11B1 (0.30) | — | |
| SCHEMBL991144 | 0.74 | — | — | |
| SCHEMBL15142636 | 0.72 | — | — | |
| SCHEMBL1973187 | 0.71 | — | — | |
| SCHEMBL2591646 | 0.71 | APP (0.31) | — | |
| SCHEMBL22518719 | 0.70 | L3MBTL1 (0.33) | CNR2 | |
| SCHEMBL22518702 | 0.70 | L3MBTL1 (0.33) | CNR2 | |
| SCHEMBL18478414 | 0.70 | CYP1A2 (0.36) | CNR2 | |
| SCHEMBL992408 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012384-A1 | TRIFLUORMETHYLOXAZINE AMIDINES AS BACE1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2016-01-28 | — | — | WO | claimed |
| WO-2016012384-A1 | TRIFLUORMETHYLOXAZINE AMIDINES AS BACE1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2016-01-28 | — | — | WO | disclosed |