Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 10/20 | 0.37 |
| ▸ | TLR2 | O60603 | 2/20 | 0.35 |
| ▸ | TLR1 | Q15399 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.34 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18668523 | 0.82 | PTGS2 (0.52) | PTGS2 | |
| SCHEMBL17470149 | 0.79 | DDR1 (0.41) | DDR1PTGS2ALOX5APFEN1KDM4E | |
| SCHEMBL17459082 | 0.78 | DDR1 (0.35) | DDR1TLR2TLR1KDM4EGAA | |
| SCHEMBL23629308 | 0.77 | DDR1 (0.42) | DDR1PTGS2SMN1; SMN2 | |
| SCHEMBL23629300 | 0.76 | PDE2A (0.36) | DDR1 | |
| SCHEMBL21925154 | 0.75 | NPC1 (0.43) | DDR1ALOX5APFEN1KDM4ELMNA | |
| SCHEMBL20434187 | 0.75 | PTGS2 (0.46) | PTGS2 | |
| SCHEMBL18668536 | 0.74 | CYP3A4 (0.41) | PTGS2ALOX5APFEN1 | |
| SCHEMBL21925165 | 0.73 | PARP1 (0.37) | DDR1ALOX5APFEN1SMN1; SMN2 | |
| SCHEMBL18908831 | 0.73 | KMT2A (0.39) | DDR1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012395-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |
| WO-2016012395-A1 | PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULPHUR CONTAINING SUBSTITUENTS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |