SCHEMBL23629308

SCHEMBL23629308

CCS(=O)(=O)c1cc(Br)cnc1-c1cn(-c2ccc(OC(F)(F)F)cc2)cn1

nearest known ligand 0.42

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DDR1 Q08345 12/20 0.42
ALDH1A1 P00352 1/20 0.35
MAPK1 P28482 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
RXRA P19793 1/20 0.34
GRIN1 Q05586 1/20 0.34
GRIN2B Q13224 1/20 0.34
PTGS2 P35354 1/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
NLRP3 Q96P20 1/20 0.34
ACLY P53396 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23629300 0.85 PDE2A (0.36) DDR1RXRAGRIN1GRIN2B
SCHEMBL23629331 0.79 RXRA (0.34) RXRAGRIN1GRIN2BPTGS2NPC1
SCHEMBL17459077 0.77 DDR1 (0.37) DDR1SMN1; SMN2PTGS2
SCHEMBL30110424 0.70 DDR1 (0.33) DDR1NPC1
SCHEMBL28962598 0.70 DDR1 (0.33) DDR1NPC1
SCHEMBL1229624 0.69 SCN5A (0.40) ALDH1A1MAPK1SMN1; SMN2RXRAGRIN1
SCHEMBL17740833 0.67 SCN5A (0.40) DDR1ALDH1A1PTGS2NPC1RAB9A
SCHEMBL17732142 0.67 DDR1 (0.33) DDR1PTGS2NPC1RAB9A
SCHEMBL18668501 0.67 RXRA (0.48) RXRAGRIN1GRIN2B
SCHEMBL20187439 0.67 DDR1 (0.37) DDR1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848362-B1 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO (JP) 2025-10-29 EP disclosed
US-12180178-B2 Heteroaryl azole compound and pest control agent NIPPON SODA CO., LTD. (JP) 2024-12-31 US disclosed
EP-4455135-A2 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2024-10-30 EP disclosed
US-20240327377-A1 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT NIPPON SODA CO., LTD. (JP) 2024-10-03 US disclosed
EP-3848362-A1 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT Nippon Soda Co., Ltd. (JP) 2021-07-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240327377-A1 HETEROARYL AZOLE COMPOUND AND PEST CONTROL AGENT INF2, CRY2, CRY1 DDR1 4619/4885ALDH1A1 4254/4885MAPK1 3416/4885
US-12180178-B2 Heteroaryl azole compound and pest control agent CRY1, CRY2, H1-2 DDR1 4142/4885ALDH1A1 4574/4885MAPK1 1530/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.