Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | MAT2A | P31153 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459261 | 0.75 | RXRA (0.40) | SMN1; SMN2POLBGLAGAAALDH1A1 | |
| SCHEMBL17459255 | 0.73 | KMT2A (0.46) | SMN1; SMN2POLBGSK3AGSK3BGAA | |
| SCHEMBL17459259 | 0.70 | CYP1A2 (0.53) | SMN1; SMN2GAAHPGDCYP1A2TSHR | |
| SCHEMBL30105442 | 0.70 | CA1 (0.33) | SMN1; SMN2POLBKDM4EALDH1A1HPGD | |
| SCHEMBL29848866 | 0.67 | CYP19A1 (0.41) | SMN1; SMN2POLBGLAGAAKDM4E | |
| SCHEMBL9623389 | 0.66 | POLB (0.56) | SMN1; SMN2POLBGSK3AGSK3BALDH1A1 | |
| SCHEMBL4212713 | 0.62 | F10 (0.56) | ALDH1A1MEN1KMT2A | |
| SCHEMBL10059745 | 0.62 | GSK3B (0.45) | GSK3AGSK3BGAAKDM4EMEN1 | |
| SCHEMBL27858439 | 0.62 | POLB (0.57) | SMN1; SMN2POLBGAAALDH1A1HPGD | |
| SCHEMBL7665875 | 0.61 | POLB (0.39) | SMN1; SMN2POLBGLAGSK3AGSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963442-B2 | Pyridones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170204081-A1 | PYRIDONES AS HERBICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-20 | — | — | US | disclosed |
| EP-3171698-A1 | PYRIDONES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016014814-A1 | PYRIDONES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204081-A1 | PYRIDONES AS HERBICIDES | CYP1B1, PNPO, CYP1A1 | SMN1; SMN2 4530/4885POLB 3371/4885GLA 1703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.