Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.38 |
| ▸ | USP2 | O75604 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459256 | 0.80 | CYP1A2 (0.44) | RXRAGRIN1GRIN2BCYP1A2CYP3A4 | |
| SCHEMBL17459254 | 0.79 | RXRA (0.53) | RXRAGRIN1GRIN2B | |
| SCHEMBL17459258 | 0.75 | SMN1; SMN2 (0.44) | CYP1A2USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL17459255 | 0.66 | KMT2A (0.46) | USP2ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL30912185 | 0.63 | SMN1; SMN2 (0.42) | RXRAGRIN1GRIN2BCYP1A2TSHR | |
| SCHEMBL11161634 | 0.62 | MEN1 (0.57) | CYP1A2USP2ALDH1A1TSHRHSD17B10 | |
| SCHEMBL9192280 | 0.61 | L3MBTL1 (0.47) | RXRAGRIN1GRIN2BCYP1A2ALDH1A1 | |
| SCHEMBL23629553 | 0.61 | MAPK14 (0.41) | CYP2C19MEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL11392451 | 0.61 | HDAC6 (0.47) | CYP1A2ALDH1A1TSHRHSD17B10CYP3A4 | |
| SCHEMBL9693794 | 0.60 | MEN1 (0.70) | CYP1A2ALDH1A1TSHRHSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9963442-B2 | Pyridones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2018-05-08 | — | — | US | claimed |
| US-20170204081-A1 | PYRIDONES AS HERBICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-20 | — | — | US | claimed |
| EP-3171698-A1 | PYRIDONES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2017-05-31 | — | — | EP | claimed |
| WO-2016014814-A1 | PYRIDONES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-01-28 | — | — | WO | claimed |
| US-9963442-B2 | Pyridones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2018-05-08 | — | — | US | disclosed |
| US-20170204081-A1 | PYRIDONES AS HERBICIDES | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-20 | — | — | US | disclosed |
| EP-3171698-A1 | PYRIDONES AS HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016014814-A1 | PYRIDONES AS HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2016-01-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170204081-A1 | PYRIDONES AS HERBICIDES | CYP1B1, PNPO, CYP1A1 | RXRA 392/4885GRIN1 709/4885GRIN2B 1720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.