Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.58 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.43 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.40 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.40 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 3/20 | 0.37 |
| ▸ | ARG2 | P78540 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17459295 | 1.00 | GSR (0.58) | GSRRNPEPCPB2GNAI3GNAO1 | |
| SCHEMBL3720346 | 0.87 | GSR (0.47) | GSRRNPEPCPB2GNAI3GNAO1 | |
| SCHEMBL5556166 | 0.84 | GSR (0.60) | GSRRNPEPCPB2GNAI3GNAO1 | |
| SCHEMBL8931572 | 0.84 | GSR (0.60) | GSRRNPEPCPB2GNAI3GNAO1 | |
| SCHEMBL30444870 | 0.81 | GSR (0.56) | GSRRNPEPCPB2GNAI3GNAO1 | |
| SCHEMBL6010251 | 0.80 | GSR (0.42) | GSRRNPEPCPB2 | |
| SCHEMBL16359366 | 0.80 | GSR (0.46) | GSRRNPEPGNAI3GNAO1GNAI1 | |
| SCHEMBL2887202 | 0.79 | GSR (0.53) | GSRRNPEPCPB2GNAI3GNAO1 | |
| SCHEMBL468723 | 0.79 | CPB2 (0.47) | GSRRNPEPCPB2 | |
| SCHEMBL468721 | 0.79 | CPB2 (0.47) | GSRRNPEPCPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207240-A1 | COLLAGEN IV REPLACEMENT | GOLDFINCH BIO, INC. | 2018-07-26 | — | — | US | disclosed |
| EP-3171889-A1 | COLLAGEN IV REPLACEMENT | GOLDFINCH BIOPHARMA, INC. (US) | 2017-05-31 | — | — | EP | disclosed |
| WO-2016014781-A1 | COLLAGEN IV REPLACEMENT | RGDI3, INC. (US) | 2016-01-28 | — | — | WO | disclosed |