SCHEMBL468723

SCHEMBL468723

CC(=O)N(O)[C@@H](CCCCN)C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CPB2 Q96IY4 7/20 0.47
GSR P00390 1/20 0.47
RNPEP Q9H4A4 1/20 0.46
FOLH1 Q04609 1/20 0.37
GABRR1 P24046 2/20 0.36
PAOX Q6QHF9 2/20 0.36
CYP2D6 P10635 1/20 0.34
NFKB1 P19838 1/20 0.34
CPB1 P15086 1/20 0.33
BLM P54132 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PLG P00747 1/20 0.33
LMNA P02545 1/20 0.33
THRB P10828 1/20 0.33
ALOX15 P16050 1/20 0.33
SLC6A2 P23975 1/20 0.33
RECQL P46063 1/20 0.33
SLC6A3 Q01959 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468721 1.00 CPB2 (0.47) CPB2GSRRNPEPFOLH1GABRR1
SCHEMBL29483412 0.94 CPB2 (0.41) CPB2GSRRNPEPGABRR1PAOX
SCHEMBL11015274 0.94 CPB2 (0.41) CPB2GSRRNPEPGABRR1PAOX
SCHEMBL28480205 0.94 CPB2 (0.41) CPB2GSRRNPEPGABRR1PAOX
SCHEMBL13176573 0.87 CPB2 (0.41) CPB2GSRRNPEPFOLH1PAOX
SCHEMBL8707562 0.86 CPB2 (0.45) CPB2GSRRNPEPFOLH1GABRR1
SCHEMBL7593236 0.83 CPB2 (0.49) CPB2GSRRNPEPFOLH1GABRR1
SCHEMBL7593232 0.83 CPB2 (0.49) CPB2GSRRNPEPFOLH1GABRR1
SCHEMBL8714819 0.83 CPB2 (0.43) CPB2GSRRNPEPFOLH1GABRR1
SCHEMBL15641943 0.81 RNPEP (0.50) CPB2GSRRNPEPFOLH1GABRR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
US-20180298065-A1 PROTEASE-RESISTANT STREPTAVIDIN EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2018-10-18 US claimed
EP-3353290-A1 PROTEASE-RESISTANT STREPTAVIDIN European Molecular Biology Laboratory (DE) 2018-08-01 EP claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
WO-2017050947-A1 PROTEASE-RESISTANT STREPTAVIDIN EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2017-03-30 WO claimed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US claimed
US-RE44302-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-06-18 US claimed
US-RE44017-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-02-19 US claimed
US-RE42902-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2011-11-08 US claimed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 US claimed
US-RE41278-E1 N-acetyl aldosamines and related N-acetyl compounds, and their topical use TRISTRATA, INC. 2010-04-27 US claimed
EP-2080504-A2 Topical composition comprising n-acetylaldosamines or n-acetylamino acids Yu, Ruey J. (US) 2009-07-22 EP claimed
EP-1639994-A2 Topical composition comprising N-acetylaldosamines or N-acetylamino acids Yu, Ruey J., Dr. (US) 2006-03-29 EP claimed
EP-1570840-A2 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2005-09-07 EP claimed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US claimed
EP-1143925-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2001-10-17 EP claimed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US claimed
WO-2000040217-B1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-10-05 WO claimed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO claimed
EP-2311452-B2 Topical composition comprising n-acetyl glucosamine YU RUEY J (US) 2020-12-30 EP disclosed
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP disclosed
US-20180298065-A1 PROTEASE-RESISTANT STREPTAVIDIN EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2018-10-18 US disclosed
EP-3353290-A1 PROTEASE-RESISTANT STREPTAVIDIN European Molecular Biology Laboratory (DE) 2018-08-01 EP disclosed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US disclosed
WO-2017050947-A1 PROTEASE-RESISTANT STREPTAVIDIN EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) 2017-03-30 WO disclosed
US-20160200880-A1 MOISTURE CURABLE COMPOSITION WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. 2016-07-14 US disclosed
EP-3039068-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS Momentive Performance Materials Inc. (US) 2016-07-06 EP disclosed
US-9333250-B2 Methods and compositions for treating bacterial infection THE JOHNS HOPKINS UNIVERSITY (US) 2016-05-10 US disclosed
WO-2015031712-A1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2015-03-05 WO disclosed
EP-2311452-B9 Topical composition comprising n-acetyl glucosamine YU RUEY J (US) 2014-12-24 EP disclosed
US-RE44302-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-06-18 US disclosed
US-RE44017-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use YU RUEY J (US) 2013-02-19 US disclosed
US-RE42902-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2011-11-08 US disclosed
EP-2311452-A1 Topical composition comprising n-acetyl glucosamine Yu, Ruey J. (US) 2011-04-20 EP disclosed
EP-2230312-A1 Probe compound for detecting and isolating enzymes and means and methods using the same Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2010-09-22 EP disclosed
US-20100136027-A1 Methods and Compositions for Treating Bacterial Infection THE JOHNS HOPKINS UNIVERSITY (US) 2010-06-03 US disclosed
US-RE41339-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2010-05-18 US disclosed
US-RE41278-E1 N-acetyl aldosamines and related N-acetyl compounds, and their topical use TRISTRATA, INC. 2010-04-27 US disclosed
EP-2080504-A2 Topical composition comprising n-acetylaldosamines or n-acetylamino acids Yu, Ruey J. (US) 2009-07-22 EP disclosed
EP-1570840-B1 Topical composition comprising n-acetylamino acids YU RUEY J (US) 2009-04-01 EP disclosed
EP-1957066-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS Chandran, V. Ravi (US) 2008-08-20 EP disclosed
WO-2007117680-A2 METHODS AND COMPOSITIONS FOR TREATING BACTERIAL INFECTION THE JOHNS HOPKINS UNIVERSITY (US) 2007-10-18 WO disclosed
WO-2007059047-A2 ACETYLATED AMINO ACIDS AS ANTI-PLATELET AGENTS, NUTRITIONAL AND VITAMIN SUPPLEMENTS CHANDRAN V RAVI (US) 2007-05-24 WO disclosed
EP-1639994-A2 Topical composition comprising N-acetylaldosamines or N-acetylamino acids Yu, Ruey J., Dr. (US) 2006-03-29 EP disclosed
EP-1570840-A2 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2005-09-07 EP disclosed
US-6524593-B1 Alleviate or improve various cosmetic conditions and dermatological disorders, skin, hair, nails TRISTRATA, INC. 2003-02-25 US disclosed
EP-1143925-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS Yu, Ruey J., Dr. (US) 2001-10-17 EP disclosed
US-6159485-A COSMETICS; SKIN DISORDERS YUGENIC LIMITED PARTNERSHIP (US) 2000-12-12 US disclosed
EP-1021189-A1 METHOD FOR THE TREATMENT OF ATHEROSCLEROSIS AND VASCULAR INJURY BY PREVENTION OF VASCULAR SMOOTH MUSCLE CELL PROLIFERATION Keystone Biomedical, Inc. (US) 2000-07-26 EP disclosed
WO-2000040217-A1 TOPICAL COMPOSITION COMPRISING N-ACETYLALDOSAMINES OR N-ACETYLAMINO ACIDS YUGENIC LIMITED PARTNERSHIP (US) 2000-07-13 WO disclosed
EP-0996450-A2 METHOD FOR THE TREATMENT OF CANCER WITH EXOCHELINS OF MYCOBACTERIUM TUBERCULOSIS Keystone Biomedical, Inc. (US) 2000-05-03 EP disclosed
WO-1998058635-A2 METHOD FOR THE TREATMENT OF CANCER WITH EXOCHELINS OF MYCOBACTERIUM TUBERCULOSIS KEYSTONE BIOMEDICAL INC. (US) 1998-12-30 WO disclosed
WO-1998034619-A1 METHOD FOR THE TREATMENT OF ATHEROSCLEROSIS AND VASCULAR INJURY BY PREVENTION OF VASCULAR SMOOTH MUSCLE CELL PROLIFERATION KEYSTONE BIOMEDICAL, INC. (US) 1998-08-13 WO disclosed
EP-0571198-B1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1997-03-19 EP disclosed
EP-0572167-B1 Cosmetic composition UNILEVER PLC (GB) 1996-10-09 EP disclosed
US-5559092-A HAIR GROWTH, GLUTAMINE DIPEPTIDE CHESEBROUGH-POND'S USA CO. DIVISION OF CONOPCO, INC. (US) 1996-09-24 US disclosed
EP-0517371-B1 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1996-01-10 EP disclosed
EP-0580409-A2 Cosmetic composition containing DOPA derivatives UNILEVER PLC (GB) 1994-01-26 EP disclosed
EP-0572167-A1 Cosmestic composition UNILEVER PLC (GB) 1993-12-01 EP disclosed
EP-0571198-A1 Cosmetic composition containing hair-growth promoter UNILEVER PLC (GB) 1993-11-24 EP disclosed
EP-0517371-A2 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1992-12-09 EP disclosed
EP-0517371-A2 Hair growth composition containing citric acid esters UNILEVER PLC (GB) 1992-12-09 EP disclosed