SCHEMBL1746007

SCHEMBL1746007

O=C1C=NN(c2ccccc2)C1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.39
RAB9A P51151 4/20 0.39
GAA P10253 4/20 0.39
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
KDM4E B2RXH2 3/20 0.36
MAPT P10636 3/20 0.36
TDP1 Q9NUW8 3/20 0.36
GLA P06280 1/20 0.36
MAPK1 P28482 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
MGLL Q99685 1/20 0.35
ALDH1A1 P00352 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
PTPN1 P18031 1/20 0.35
CYP1A2 P05177 1/20 0.35
CHRM2 P08172 1/20 0.35
CYP3A4 P08684 1/20 0.35
CHRM1 P11229 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8658538 0.73 MAPT (0.43) MEN1KMT2AMAPTTDP1MAPK1
SCHEMBL10469540 0.73 SMN1; SMN2 (0.44) GAAKDM4EMAPTMAPK1ALDH1A1
SCHEMBL6515952 0.69 CHRNA7 (0.31)
SCHEMBL4282419 0.67 GAA (0.43) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL3365280 0.64 NPC1 (0.41) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL3820724 0.64 MAPT (0.44) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL3946803 0.64 MAOB (0.40) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL9466928 0.64 KDM4E (0.38) NPC1RAB9AGAAMEN1KMT2A
SCHEMBL11287114 0.64 CYP2C19 (0.35) GAAMEN1KMT2AKDM4EMAPT
SCHEMBL6836736 0.63 KDM4E (0.44) NPC1RAB9AGAAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997242-B Substituted phenyl pyrazolone derivative, preparation and application 浙江大学 2020-10-20 CN claimed
US-20230407150-A1 ONE COMPONENT (1K) CURABLE ADHESIVE COMPOSITION HENKEL AG & CO KGAA (DE) 2023-12-21 US disclosed
EP-4050040-A1 ONE COMPONENT (1K) CURABLE ADHESIVE COMPOSITION Henkel AG & Co. KGaA (DE) 2022-08-31 EP disclosed
EP-3174932-B1 CURE ACCELERATORS FOR ANAEROBIC CURABLE COMPOSITIONS Henkel IP & Holding GmbH (DE) 2021-06-09 EP disclosed
CN-108997242-B Substituted phenyl pyrazolone derivative, preparation and application 浙江大学 2020-10-20 CN disclosed
EP-3209702-B1 ANAEROBIC CURABLE COMPOSITIONS HAVING NOVOLAC VINYL ESTERS Henkel IP & Holding GmbH (DE) 2018-12-12 EP disclosed
US-9957344-B2 Anaerobic curable compositions having novolac vinyl esters Henkel IP & Holding GmbH (DE) 2018-05-01 US disclosed
CN-107124882-A Novel compounds for cognitive improvement 基础应用医学研究基金会 2017-09-01 CN disclosed
EP-3209702-A1 ANAEROBIC CURABLE COMPOSITIONS HAVING NOVOLAC VINYL ESTERS Henkel IP & Holding GmbH (DE) 2017-08-30 EP disclosed
US-20170226256-A1 ANAEROBIC CURABLE COMPOSITIONS HAVING NOVOLAC VINYL ESTERS HENKEL AG & CO. KGAA (DE) 2017-08-10 US disclosed
EP-0504609-B1 Processing solution for silver halide color photographic materials and method of processing the materials with use of the processing solution FUJI PHOTO FILM CO LTD (JP) 1995-07-19 EP disclosed
US-5270148-A Processing solution for silver halide color photographic materials and method for processing the materials with the processing solution FUJI PHOTO FILM CO., LTD. (JP) 1993-12-14 US disclosed
EP-0519190-A1 Processing solution for silver halide color photographic materials and method for processing the materials with the processing solution FUJI PHOTO FILM CO., LTD. (JP) 1992-12-23 EP disclosed
EP-0504609-A2 Processing solution for silver halide color photographic materials and method of processing the materials with use of the processing solution FUJI PHOTO FILM CO., LTD. (JP) 1992-09-23 EP disclosed
EP-0240964-B1 REAGENT FOR THE ENZYMATIC DETERMINATION OF PRIMARY C1-C4 ALCOHOLS AND RELATED METHOD BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1992-07-15 EP disclosed
US-4996138-A Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1991-02-26 US disclosed
CN-1044656-A Pyrazolopyridine compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1990-08-15 CN disclosed
EP-0362734-A2 Silver halide photographic light-sensitive material KONICA CORPORATION (JP) 1990-04-11 EP disclosed
EP-0240964-A1 Reagent for the enzymatic determination of primary C1-C4 alcohols and related method BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) 1987-10-14 EP disclosed
US-RE29498-E PEROXIDASE ENZYME SYSTEM Istituto Sieroterapico e Vaccinogeno Toscano "SCLAVO", S.p.A. (IT) 1977-12-20 US disclosed