SCHEMBL3365280

SCHEMBL3365280

NC1=NN(c2ccccc2)CC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.41
RAB9A P51151 3/20 0.41
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 3/20 0.38
MAPT P10636 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
GAA P10253 3/20 0.38
ALDH1A1 P00352 2/20 0.38
GLA P06280 1/20 0.38
MAPK1 P28482 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
CYP1A2 P05177 1/20 0.37
CHRM2 P08172 1/20 0.37
CYP3A4 P08684 1/20 0.37
CHRM1 P11229 1/20 0.37
TSHR P16473 1/20 0.37
PTGS1 P23219 1/20 0.37
DRD3 P35462 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3946803 0.77 MAOB (0.40) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL3820724 0.77 MAPT (0.44) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL9466928 0.77 KDM4E (0.38) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL5425655 0.76 MAPT (0.43) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL6836736 0.76 KDM4E (0.44) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL7759443 0.74 POLB (0.44) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL11026530 0.72 HSP90AA1 (0.38) NPC1RAB9AMEN1KMT2AKDM4E
Dimethylamine SCHEMBL10491493 0.70 KDM4E (0.40) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL3813689 0.70 POLB (0.37) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL11542871 0.70 SHMT2 (0.43) NPC1RAB9AMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1413286-B1 Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent OREAL (FR) 2009-04-22 EP claimed
WO-2007071688-A1 COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, A PARTICULAR OXIDATION BASE AND A COUPLER L'ORÉAL (FR) 2007-06-28 WO claimed
EP-1413286-A1 Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent L'OREAL (FR) 2004-04-28 EP claimed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US claimed
CN-116178266-A Cyano pyrazolone heterobifunctional reagent and application thereof in construction of sugar chip 西北大学 2023-05-30 CN disclosed
EP-2091752-B1 METHOD OF PRODUCING AN INFORMATION CARRIER AGFA GEVAERT NV (BE) 2010-10-06 EP disclosed
EP-1413286-B1 Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent OREAL (FR) 2009-04-22 EP disclosed
US-20080136160-A1 METHOD OF PRODUCING AN INFORMATION CARRIER AGFA-GEVAERT (BE) 2008-06-12 US disclosed
WO-2007071688-A1 COMPOSITION FOR DYEING KERATIN FIBRES WITH A TETRAAZAPENTAMETHINE CATIONIC DIRECT DYE, A PARTICULAR OXIDATION BASE AND A COUPLER L'ORÉAL (FR) 2007-06-28 WO disclosed
US-20060241225-A1 Laser activated thermochromic compositions FLEXCON COMPANY, INC. 2006-10-26 US disclosed
EP-1459732-A1 Dye composition comprising at least one heterocyclic oxidation base and at least one 2,3,5-triaminopyridine as coupler L'OREAL (FR) 2004-09-22 EP disclosed
EP-1413286-A1 Dyeing composition comprising at least one heterocyclic oxidation base and at least one substituted 2,3-diaminopyridine as a coupling agent L'OREAL (FR) 2004-04-28 EP disclosed
US-3979320-A Liquid crystal composition HODOGAYA CHEMICAL CO., LTD. (JA) 1976-09-07 US disclosed