SCHEMBL6836736

SCHEMBL6836736

O=C1CN(c2ccccc2)N=C1c1ccccc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.44
MAPT P10636 6/20 0.44
TDP1 Q9NUW8 4/20 0.44
L3MBTL1 Q9Y468 3/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
GLA P06280 2/20 0.44
MAPK1 P28482 2/20 0.44
MEN1 O00255 5/20 0.36
KMT2A Q03164 5/20 0.36
GAA P10253 5/20 0.36
ALDH1A1 P00352 4/20 0.36
CYP1A2 P05177 1/20 0.36
CHRM2 P08172 1/20 0.36
CYP3A4 P08684 1/20 0.36
CHRM1 P11229 1/20 0.36
TSHR P16473 1/20 0.36
PTGS1 P23219 1/20 0.36
DRD3 P35462 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylamine SCHEMBL10491493 0.93 KDM4E (0.40) KDM4EMAPTTDP1L3MBTL1NPC1
Diethylamine SCHEMBL10491539 0.88 CES2 (0.37) KDM4EMAPTTDP1L3MBTL1NPC1
SCHEMBL28512599 0.82 SRC (0.34) KDM4EMAPTTDP1L3MBTL1NPC1
SCHEMBL3946803 0.76 MAOB (0.40) KDM4EMAPTTDP1L3MBTL1NPC1
SCHEMBL11124893 0.76 KMT2A (0.39) KDM4EMAPTTDP1L3MBTL1NPC1
SCHEMBL213868 0.76 GABRA1 (0.41) KDM4EKMT2AGAAALDH1A1MAOB
SCHEMBL9466928 0.76 KDM4E (0.38) KDM4EMAPTTDP1L3MBTL1NPC1
SCHEMBL3820724 0.76 MAPT (0.44) KDM4EMAPTTDP1L3MBTL1NPC1
SCHEMBL3365280 0.76 NPC1 (0.41) KDM4EMAPTTDP1L3MBTL1NPC1
SCHEMBL5425655 0.74 MAPT (0.43) KDM4EMAPTTDP1L3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040107516-A1 Hair colouring compositions and their use THE PROCTER & GAMBLE COMPANY 2004-06-10 US claimed
WO-2024048230-A1 SCINTILLATOR PANEL, RADIATION DETECTOR AND RADIOGRAPHIC EXAMINATION DEVICE EACH USING SAME, AND METHOD FOR MANUFACTURING RADIATION DETECTOR 東レ株式会社 2024-03-07 WO disclosed
US-20230408711-A1 SCINTILLATOR PANEL, RADIATION DETECTOR, RADIATION INSPECTION DEVICE, AND METHOD FOR PRODUCING SCINTILLATOR PANEL TORAY INDUSTRIES, INC. (JP) 2023-12-21 US disclosed
EP-4270062-A1 SCINTILLATOR PANEL, RADIATION DETECTOR, RADIATION INSPECTION DEVICE, AND METHOD FOR PRODUCING SCINTILLATOR PANEL Toray Industries, Inc. (JP) 2023-11-01 EP disclosed
EP-3916069-B1 SCINTILLATOR PANEL, X-RAY DETECTOR USING SAME, AND X-RAY FLUOROSCOPY DEVICE TORAY INDUSTRIES (JP) 2023-10-11 EP disclosed
US-11280920-B2 Scintillator panel, X-ray detector using same, and X-ray fluoroscopy device TORAY INDUSTRIES, INC. (JP) 2022-03-22 US disclosed
EP-3916069-A1 SCINTILLATOR PANEL, X-RAY DETECTOR USING SAME, AND X-RAY FLUOROSCOPY DEVICE Toray Industries, Inc. (JP) 2021-12-01 EP disclosed
US-20210173100-A1 SCINTILLATOR PANEL AND X-RAY DETECTOR USING SAME TORAY INDUSTRIES, INC. (JP) 2021-06-10 US disclosed
EP-0072960-B1 1,5-DIPHENYLPYRAZOLIN-3-ONE COMPOUNDS, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS Kali-Chemie Pharma GmbH (DE) 1989-06-07 EP disclosed
US-4515944-A ANTIALLERGIC KALI-CHEMIE PHARMA GMBH (DE) 1985-05-07 US disclosed
US-4442102-A ANTIALLERGIC KALI-CHEMIE PHARMA GMBH (DE) 1984-04-10 US disclosed
EP-0072960-A2 1,5-Diphenylpyrazolin-3-one compounds, process and intermediates for their preparation and medicines containing these compounds Kali-Chemie Pharma GmbH (DE) 1983-03-02 EP disclosed
US-4146540-A Pyrazole compounds as stabilizers for organic materials SANDOZ LTD. (CH) 1979-03-27 US disclosed
US-4008200-A Method of stabilizing organic materials employing pyrazole compounds and stabilized compositions thereof SANDOZ LTD. (CH) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040107516-A1 Hair colouring compositions and their use TYR, TET1, TET2 KDM4E 84/4885MAPT 3755/4885TDP1 976/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.