Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
| ▸ | CETP | P11597 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.34 |
| ▸ | GJB2 | P29033 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745769 | 1.00 | MAPK1 (0.39) | MAPK1GBA1SLC2A1OGACETP | |
| SCHEMBL1747616 | 0.94 | OGA (0.37) | MAPK1SLC2A1OGAADORA2AADORA2B | |
| SCHEMBL1746439 | 0.94 | OGA (0.37) | MAPK1SLC2A1OGAADORA2AADORA2B | |
| SCHEMBL14939309 | 0.94 | OGA (0.37) | MAPK1SLC2A1OGAADORA2AADORA2B | |
| SCHEMBL22659911 | 0.94 | OGA (0.37) | MAPK1SLC2A1OGAADORA2AADORA2B | |
| SCHEMBL13157186 | 0.81 | CETP (0.46) | MAPK1CETPPTPN1GJB2 | |
| SCHEMBL13157187 | 0.81 | CETP (0.46) | MAPK1CETPPTPN1GJB2 | |
| SCHEMBL1746034 | 0.81 | CETP (0.46) | MAPK1CETPPTPN1GJB2 | |
| SCHEMBL1745771 | 0.81 | CETP (0.46) | MAPK1CETPPTPN1GJB2 | |
| SCHEMBL1747110 | 0.80 | GBA1 (0.43) | MAPK1GBA1SLC2A1CETPPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563337-B1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | SALAMA ZOSER B (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2563337-A1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | Salama, Zoser B. (DE) | 2013-03-06 | — | — | EP | disclosed |
| EP-2384743-A1 | Siosomal formulation for intracellular delivery and targeting of therapeutic agents | Salama, Zoser B. (DE) | 2011-11-09 | — | — | EP | disclosed |
| WO-2011134675-A1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | SALAMA ZOSER B (DE) | 2011-11-03 | — | — | WO | disclosed |