SCHEMBL1745771

SCHEMBL1745771

CCCCCCCCCC[Si](C)(C)O[C@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1O

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CETP P11597 1/20 0.46
▸ MAPK1 P28482 1/20 0.45
▸ PTPN1 P18031 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ GJB2 P29033 2/20 0.41
▸ MAPT P10636 1/20 0.41
▸ TLR4 O00206 1/20 0.39
▸ LGALS8 O00214 1/20 0.39
▸ LGALS3 P17931 1/20 0.39
▸ LGALS4 P56470 1/20 0.39
▸ GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1746034 1.00 CETP (0.46) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL13157186 1.00 CETP (0.46) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL13157187 1.00 CETP (0.46) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL17651845 0.94 L3MBTL1 (0.44) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL1746441 0.94 L3MBTL1 (0.44) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL1747620 0.94 L3MBTL1 (0.44) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL5309010 0.94 L3MBTL1 (0.44) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL13157184 0.94 L3MBTL1 (0.44) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL14939003 0.94 L3MBTL1 (0.44) CETPMAPK1PTPN1L3MBTL1GJB2
SCHEMBL1746033 0.81 MAPK1 (0.39) CETPMAPK1PTPN1GJB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2563337-B1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2017-07-26 — — EP disclosed
EP-2563337-A1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE Salama, Zoser B. (DE) 2013-03-06 — — EP disclosed
EP-2384743-A1 Siosomal formulation for intracellular delivery and targeting of therapeutic agents Salama, Zoser B. (DE) 2011-11-09 — — EP disclosed
WO-2011134675-A1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2011-11-03 — — WO disclosed
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