SCHEMBL1746439

SCHEMBL1746439

CCCC[Si](C)(C)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ OGA O60502 5/20 0.37
▸ MAPK1 P28482 2/20 0.35
▸ HEXB P07686 2/20 0.34
▸ HEXA P06865 1/20 0.34
▸ SLC2A1 P11166 1/20 0.34
▸ PYGB P11216 1/20 0.33
▸ ADORA2A P29274 1/20 0.32
▸ ADORA2B P29275 1/20 0.32
▸ SLC29A1 Q99808 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22659911 1.00 OGA (0.37) OGAMAPK1HEXBHEXASLC2A1
SCHEMBL14939309 1.00 OGA (0.37) OGAMAPK1HEXBHEXASLC2A1
SCHEMBL1747616 1.00 OGA (0.37) OGAMAPK1HEXBHEXASLC2A1
SCHEMBL1745769 0.94 MAPK1 (0.39) OGAMAPK1SLC2A1ADORA2AADORA2B
SCHEMBL1746033 0.94 MAPK1 (0.39) OGAMAPK1SLC2A1ADORA2AADORA2B
SCHEMBL13157184 0.80 L3MBTL1 (0.44) MAPK1
SCHEMBL5309010 0.80 L3MBTL1 (0.44) MAPK1
SCHEMBL14939003 0.80 L3MBTL1 (0.44) MAPK1
SCHEMBL1746441 0.80 L3MBTL1 (0.44) MAPK1
SCHEMBL17651845 0.80 L3MBTL1 (0.44) MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020232194-A1 METHODS FOR GLYCOSYLATION THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) 2020-11-19 — — WO disclosed
EP-2563337-B1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2017-07-26 — — EP disclosed
EP-2384743-A1 Siosomal formulation for intracellular delivery and targeting of therapeutic agents Salama, Zoser B. (DE) 2011-11-09 — — EP disclosed
Send feedback