SCHEMBL1746044

SCHEMBL1746044

CCCCCCCCCCCCCCCCCC(=O)O[Si](C)(C)OC(=O)CCCCCCCCCCCCCCCCC

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.57
LMNA P02545 2/20 0.53
PAM P19021 2/20 0.52
CES2 O00748 3/20 0.50
CES1 P23141 3/20 0.50
MAPT P10636 2/20 0.50
MAPK1 P28482 1/20 0.50
TSHR P16473 5/20 0.48
PPARG P37231 6/20 0.48
PPARD Q03181 6/20 0.48
PPARA Q07869 6/20 0.48
HDAC11 Q96DB2 5/20 0.48
GPR84 Q9NQS5 4/20 0.48
ALDH1A1 P00352 2/20 0.48
TLR2 O60603 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
FABP4 P15090 2/20 0.48
PTPN1 P18031 2/20 0.48
SLC22A6 Q4U2R8 1/20 0.48
SLC22A8 Q8TCC7 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1746235 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL1747070 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL1747414 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL5077571 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL1747375 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL1747009 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL1747371 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL1747158 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL1747104 1.00 DGKA (0.57) DGKALMNAPAMCES2CES1
SCHEMBL6554418 0.91 DGKA (0.57) DGKALMNAPAMCES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3509706-B1 METHOD FOR INCREASING LIPOLYSIS USING A COMPOSITION COMPRISING BIOACTIVE NELUMBO NUCIFERA (LOTUS) EXTRACT ISP INVESTMENTS LLC (US) 2021-11-03 EP claimed
EP-1948196-B1 USE OF TETRAORGANOSILICON COMPOUNDS SALAMA ZOSER B (DE) 2012-12-26 EP claimed
US-20250161195-A1 METHOD FOR OBTAINING PLANT EXTRACTS COMPRISING AN AUTOFERMENTATION STEP, COMPOSITIONS COMPRISING SUCH EXTRACTS AND COMETIC USES THEREOF ISP INVESTMENTS LLC (US) 2025-05-22 US disclosed
US-20230364004-A1 STABLE COMPOSITIONS CONTAINING A CANNABINOID Angrow Company Limited (US) 2023-11-16 US disclosed
US-11503840-B2 Peptide and saccharide hydrolysate of cocoa beans, cosmetic compositions containing same, and cosmetic uses of same ISP Investments LLC. (US) 2022-11-22 US disclosed
CN-113747949-A O/W type low viscosity emulsified composition containing adenosine phosphate 大塚制药株式会社 2021-12-03 CN disclosed
CN-113710330-A O/W type high viscosity emulsified composition containing adenosine phosphate 大塚制药株式会社 2021-11-26 CN disclosed
EP-3509706-B1 METHOD FOR INCREASING LIPOLYSIS USING A COMPOSITION COMPRISING BIOACTIVE NELUMBO NUCIFERA (LOTUS) EXTRACT ISP INVESTMENTS LLC (US) 2021-11-03 EP disclosed
US-11045669-B2 Hydroalcoholic extract of Schinus molle, cosmetic compositions comprising the same and cosmetic uses thereof ISP INVESTMENTS LLC (US) 2021-06-29 US disclosed
US-20210106022-A1 PEPTIDE AND SACCHARIDE HYDROLYSATE OF COCOA BEANS, COSMETIC COMPOSITIONS CONTAINING SAME, AND COSMETIC USES OF SAME ISP Investments LLC. (US) 2021-04-15 US disclosed
US-10932477-B2 Peptide and saccharide hydrolysate of cocoa beans, cosmetic compositions containing same, and cosmetic uses of same ISP INVESTMENTS LLC (US) 2021-03-02 US disclosed
EP-2384743-A1 Siosomal formulation for intracellular delivery and targeting of therapeutic agents Salama, Zoser B. (DE) 2011-11-09 EP disclosed
WO-2011134675-A1 CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE SALAMA ZOSER B (DE) 2011-11-03 WO disclosed
US-20100247578-A1 CARRIER SYSTEM FOR BIOLOGICAL AGENTS CONTAINING ORGANOSILICON COMPOUNDS AND USES THEREOF SALAMA ZOSER B 2010-09-30 US disclosed
EP-1948196-A2 USE OF TETRAORGANOSILICON COMPOUNDS Salama, Zoser B. (DE) 2008-07-30 EP disclosed
US-7241853-B2 Printing processes employing intermediate transfer with molten intermediate transfer materials XEROX CORPORATION (US) 2007-07-10 US disclosed
WO-2007051462-A2 USE OF TETRAORGANOSILICON COMPOUNDS SALAMA ZOSER B (DE) 2007-05-10 WO disclosed
US-5738857-A Cosmetic compositions comprising organosiloxanes WACKER-CHEMIE GMBH (DE) 1998-04-14 US disclosed
EP-0483465-B1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs SALAMA ZOSER BOULIS DR (DE) 1995-08-02 EP disclosed
EP-0483465-A1 Long chain di(acyloxy)dialkylsilanes, di(acyloxy)diarylsilanes, di(acyloxy)dialkoxysilanes, and tetra(acyloxy)silanes, process for their preparation, their use for the preparation of vesicles, so produced vesicles and their use as vehicles for drugs Salama, Zoser Boulis, Dr. (DE) 1992-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247578-A1 CARRIER SYSTEM FOR BIOLOGICAL AGENTS CONTAINING ORGANOSILICON COMPOUNDS AND USES THEREOF EXOSC5, EXOSC9, SSB DGKA 3104/4885LMNA 1390/4885PAM 4229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.