Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MLNR | O43193 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL174914 | 0.93 | HTR2C (0.45) | MLNRCYP2D6HTR2CHTR2BHTR2A | |
| Adipic Acid SCHEMBL173690 | 0.88 | HTR2C (0.42) | MLNRCYP2D6HTR2CHTR2BHTR2A | |
| Malonic Acid SCHEMBL173339 | 0.85 | HTR2C (0.45) | MLNRCYP2D6HTR2CHTR2BHTR2A | |
| Glycolic Acid SCHEMBL174349 | 0.85 | HTR2C (0.45) | MLNRCYP2D6HTR2CHTR2BHTR2A | |
| SCHEMBL162032 | 0.81 | HTR2C (0.57) | MLNRCYP2D6HTR2CHTR2BHTR2A | |
| Glutamic Acid SCHEMBL175044 | 0.80 | GRIK1 (0.43) | MLNRCYP2D6HTR2CHTR2BHTR2A | |
| Alpha-Ketoglutaric Acid SCHEMBL16464850 | 0.80 | HTR2C (0.53) | HTR2CHTR2BALDH1A1DRD2DRD1 | |
| Bromide SCHEMBL174563 | 0.80 | HTR2C (0.55) | MLNRCYP2D6HTR2CHTR2BHTR2A | |
| Nitric Acid SCHEMBL174071 | 0.79 | MLNR (0.47) | MLNRCYP2D6HTR2CHTR2BHTR2A | |
| Phosphoric Acid SCHEMBL174207 | 0.79 | HTR2C (0.47) | MLNRCYP2D6HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611449-A1 | ADMINISTRATION OF LORCASERIN TO INDIVIDUALS WITH RENAL IMPAIRMENT | Arena Pharmaceuticals, Inc. (US) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012030939-A1 | ADMINISTRATION OF LORCASERIN TO INDIVIDUALS WITH RENAL IMPAIRMENT | ARENA PHARMACEUTICALS, INC. (US) | 2012-03-08 | — | — | WO | disclosed |