Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.43 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | CDC7 | O00311 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2614938 | 0.83 | RAB9A (0.47) | CYP11B1CYP11B2NPC1RAB9AMAPT | |
| SCHEMBL18850044 | 0.83 | CYP11B1 (0.50) | CYP11B1CYP11B2NPC1RAB9AMAPT | |
| SCHEMBL25524135 | 0.79 | CYP11B1 (0.47) | CYP11B1CYP11B2NPC1RAB9AMAPT | |
| SCHEMBL2614937 | 0.79 | SCN10A (0.49) | CYP11B1CYP11B2NPC1RAB9AMAPT | |
| SCHEMBL10165308 | 0.79 | CYP11B2 (0.55) | CYP11B1CYP11B2NPC1RAB9AKDM4E | |
| SCHEMBL2614930 | 0.79 | CYP11B2 (0.48) | CYP11B1CYP11B2LMNAIDO1 | |
| SCHEMBL3422108 | 0.78 | CYP11B1 (0.43) | CYP11B1CYP11B2CYP2A6GRM5 | |
| SCHEMBL13097166 | 0.78 | CYP2A6 (0.68) | BRAFMAPTKDM4ELMNASMN1; SMN2 | |
| SCHEMBL28740963 | 0.76 | CYP2A6 (0.51) | CYP11B1CYP11B2NPC1KDM4ECYP2A6 | |
| SCHEMBL27451301 | 0.76 | CHEK1 (0.59) | CYP11B1CYP11B2DYRK1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230293519-A1 | INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS | PLIANT THERAPEUTICS INC (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230293519-A1 | INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS | PLIANT THERAPEUTICS INC (US) | 2023-09-21 | — | — | US | disclosed |
| US-9666807-B2 | Organic light emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-05-30 | — | — | US | disclosed |
| US-9666807-B2 | Organic light emitting device | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-05-30 | — | — | US | disclosed |
| US-20160028017-A1 | ORGANIC LIGHT EMITTING DEVICE | SAMSUNG DISPLAY CO., LTD. (KR) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293519-A1 | INTEGRIN INHIBITORS AND USES THEREOF IN COMBINATION WITH OTHER AGENTS | ITGB6, ITGA5, ITGAV | CYP11B1 4804/4885CYP11B2 4691/4885DYRK1A 4086/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.