SCHEMBL17463182

SCHEMBL17463182

c1ccc(-c2ccncc2[Si](c2ccccc2)(c2ccccc2)c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ATM Q13315 1/20 0.41
DYRK1A Q13627 2/20 0.36
TNF P01375 1/20 0.32
CDK4 P11802 1/20 0.32
CDK6 Q00534 1/20 0.32
CYP1A2 P05177 4/20 0.32
METAP2 P50579 1/20 0.32
KMT2A Q03164 2/20 0.32
IL1R1 P14778 1/20 0.32
RPS6KA3 P51812 1/20 0.32
KCNH2 Q12809 2/20 0.31
GSK3B P49841 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
PTGER4 P35408 1/20 0.31
AOC3 Q16853 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17463188 0.91 L3MBTL1 (0.41) L3MBTL1KDM4EATMDYRK1ATNF
SCHEMBL17463166 0.87 L3MBTL1 (0.46) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL22086420 0.83 KDM4E (0.34) L3MBTL1KDM4EATMCDK4CDK6
SCHEMBL17461213 0.82 L3MBTL1 (0.49) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17463193 0.81 KDM4E (0.51) L3MBTL1KDM4EATMCDK4CDK6
SCHEMBL17463351 0.81 CDK4 (0.40) L3MBTL1KDM4EATMDYRK1ACDK4
SCHEMBL17463185 0.81 KDM4E (0.40) L3MBTL1KDM4EATMCYP1A2KMT2A
SCHEMBL17461239 0.81 KMT2A (0.44) L3MBTL1KDM4EATMKMT2AIL1R1
SCHEMBL17463202 0.81 L3MBTL1 (0.47) L3MBTL1KDM4EATMCDK4CDK6
SCHEMBL17463169 0.81 L3MBTL1 (0.47) L3MBTL1KDM4EATMKMT2AIL1R1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2016-01-28 US disclosed
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD., (KR) 2016-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160028030-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CCNE2, CCNE1 L3MBTL1 863/4885KDM4E 1882/4885ATM 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.