SCHEMBL17464262

SCHEMBL17464262

Nc1ccc(O)c2c(O)c3c(c(O)c12)C(=O)CCC3=O

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A1 P68400 1/20 0.42
CSNK2A3 Q8NEV1 1/20 0.42
PIM1 P11309 1/20 0.39
MEN1 O00255 2/20 0.37
POLB P06746 2/20 0.37
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
PABPC1 P11940 1/20 0.37
HPGD P15428 1/20 0.37
CSNK1A1 P48729 1/20 0.37
CSNK1D P48730 1/20 0.37
BLM P54132 1/20 0.37
MCL1 Q07820 1/20 0.37
PLEC Q15149 1/20 0.37
CSNK1G1 Q9HCP0 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
NQO1 P15559 1/20 0.34
AURKA O14965 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17464273 0.92 CSNK2A2 (0.39) CSNK2A2CSNK2BCSNK2A1CSNK2A3PIM1
SCHEMBL17464265 0.88 PIM1 (0.50) CSNK2A2CSNK2BCSNK2A1CSNK2A3PIM1
SCHEMBL17464267 0.78 MAOA (0.40) PIM1MEN1POLBKMT2ASMN1; SMN2
SCHEMBL16089352 0.75 SELL (0.46) CSNK2A1PIM1MEN1KMT2ASMN1; SMN2
SCHEMBL9404932 0.75 CSNK2A2 (0.52) CSNK2A2CSNK2BCSNK2A1CSNK2A3PIM1
SCHEMBL17464269 0.72 SRC (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL10896774 0.71 CSNK2A2 (0.38) CSNK2A2CSNK2BCSNK2A1CSNK2A3MEN1
SCHEMBL17464268 0.70 MAPT (0.42) MEN1POLBKMT2ASMN1; SMN2HPGD
SCHEMBL13568681 0.70 TXNRD1 (0.50) CSNK2A2CSNK2BCSNK2A1CSNK2A3PIM1
SCHEMBL5606134 0.70 PIM1 (0.50) CSNK2A2CSNK2BCSNK2A1CSNK2A3PIM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9804512-B2 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-10-31 US disclosed
US-9804512-B2 Electrophotographic photosensitive member, method for producing electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus CANON KABUSHIKI KAISHA (JP) 2017-10-31 US disclosed
US-20160026099-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-01-28 US disclosed
US-20160026099-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, METHOD FOR PRODUCING ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2016-01-28 US disclosed