Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6368415 | 0.88 | CYP3A4 (0.37) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL7413884 | 0.88 | CYP3A4 (0.37) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL9225021 | 0.87 | TSHR (0.39) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL1747000 | 0.87 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL17277085 | 0.86 | ALDH1A1 (0.44) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL1076767 | 0.84 | ALDH1A1 (0.45) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL1746363 | 0.84 | ALDH1A1 (0.45) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL3111388 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL597825 | 0.83 | ALDH1A1 (0.44) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL598112 | 0.83 | ALDH1A1 (0.44) | ALDH1A1CYP1A2TSHRUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563758-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | LACER, S.A. (ES) | 2013-03-06 | — | — | EP | disclosed |
| US-20130046012-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | LACER, S.A. (ES) | 2013-02-21 | — | — | US | disclosed |
| WO-2011135007-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | LACER, S.A. (ES) | 2011-11-03 | — | — | WO | disclosed |
| EP-2383255-A1 | New compounds, synthesis and use thereof in the treatment of pain | LACER, S.A. (ES) | 2011-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130046012-A1 | NEW COMPOUNDS, SYNTHESIS AND USE THEREOF IN THE TREATMENT OF PAIN | OPRL1, OPRK1, TRPV1 | ALDH1A1 575/4885CYP1A2 113/4885TSHR 4063/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.