Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 6/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 5/20 | 0.34 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746373 | 0.91 | PDE4B (0.39) | GSK3BCYP2C9PDE4BCYP1A2ALDH1A1 | |
| SCHEMBL8443924 | 0.78 | BUB1 (0.44) | PDE4BBUB1 | |
| SCHEMBL1746587 | 0.72 | PDE4B (0.39) | CYP2C9PDE4BLMNAMAPK1CYP1A2 | |
| SCHEMBL8442662 | 0.72 | BUB1 (0.37) | CYP2C9PDE4BBUB1CYP1A2ALDH1A1 | |
| SCHEMBL8442660 | 0.70 | USP30 (0.39) | PDE4BBUB1 | |
| SCHEMBL8446562 | 0.70 | PDE4B (0.41) | PDE4BBUB1LMNAALDH1A1 | |
| SCHEMBL1746280 | 0.69 | ADORA1 (0.38) | GSK3BCYP2C9PDE4BLMNAMAPK1 | |
| SCHEMBL19664854 | 0.64 | KMO (0.42) | MAPK1ALDH1A1NPC1 | |
| SCHEMBL17847603 | 0.63 | BUB1 (0.50) | BUB1 | |
| SCHEMBL19714885 | 0.62 | CDC7 (0.64) | AKT1GSK3BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |