Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | BPTF | Q12830 | 1/20 | 0.36 |
| ▸ | VCP | P55072 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | SDHB | P21912 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747649 | 0.90 | POLB (0.39) | PDE4BPOLBLMNAHTTKMT2A | |
| SCHEMBL1746282 | 0.88 | PDE4B (0.35) | PDE4B | |
| SCHEMBL1746227 | 0.88 | PDE4B (0.43) | PDE4BVCPHSD17B10LMNAKMT2A | |
| SCHEMBL8446595 | 0.87 | BUB1 (0.44) | PDE4BUSP30ACACBACACA | |
| SCHEMBL1747642 | 0.84 | NPSR1 (0.41) | PDE4BVCPHSD17B10LMNAHPGD | |
| SCHEMBL1746373 | 0.81 | PDE4B (0.39) | PDE4BUSP30POLBHSD17B10HTT | |
| SCHEMBL1747304 | 0.78 | LMNA (0.35) | PDE4BBPTFVCPPOLBHSD17B10 | |
| SCHEMBL8443971 | 0.77 | USP30 (0.38) | PDE4BUSP30POLBKMT2AMEN1 | |
| SCHEMBL8442707 | 0.77 | PDE4B (0.41) | PDE4BUSP30HSD17B10HPGDKMT2A | |
| SCHEMBL8443926 | 0.76 | GPR119 (0.37) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |