Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746373 | 0.77 | PDE4B (0.39) | ADORA1ADORA2ACYP2C9KDM4EMEN1 | |
| SCHEMBL1747614 | 0.68 | POLB (0.39) | ADORA1ADORA2AKDM4EMEN1KMT2A | |
| SCHEMBL8443924 | 0.68 | BUB1 (0.44) | ADORA1ADORA2APDE4B | |
| SCHEMBL8445470 | 0.67 | ABCB1 (0.36) | ADORA1ADORA2APDE4BALDH1A1MAPK1 | |
| SCHEMBL1746137 | 0.60 | TSHR (0.48) | CYP2C9MEN1KMT2APOLBPDE4B | |
| SCHEMBL28020209 | 0.56 | TSHR (0.43) | ADORA1ADORA2AKDM4EMEN1KMT2A | |
| SCHEMBL1735055 | 0.56 | MCL1 (0.50) | ADORA1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13133556 | 0.56 | MAPT (0.58) | ADORA1ADORA2AKDM4EMEN1KMT2A | |
| SCHEMBL9619520 | 0.56 | MEN1 (0.50) | ADORA1ADORA2AKDM4EMEN1KMT2A | |
| SCHEMBL1733453 | 0.55 | KDM4E (0.57) | CYP2C9KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |