Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADK | P55263 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1746587 | 0.70 | PDE4B (0.39) | TSHRHPGDTP53POLBLMNA | |
| SCHEMBL1746476 | 0.69 | AKT1 (0.37) | LMNAALDH1A1CYP1A2CYP2C9PDE4B | |
| SCHEMBL28227385 | 0.64 | TSHR (0.71) | TSHRHPGDTP53USP2POLB | |
| SCHEMBL28948723 | 0.63 | CCNA2 (0.41) | KMT2AMEN1 | |
| SCHEMBL1747649 | 0.63 | POLB (0.39) | POLBLMNAKMT2AMEN1ALDH1A1 | |
| SCHEMBL3118565 | 0.62 | MTHFD2 (0.50) | TSHR | |
| SCHEMBL8805074 | 0.62 | HTR2A (0.35) | KMT2AMEN1 | |
| SCHEMBL3258197 | 0.61 | TSHR (0.80) | TSHRHPGDTP53USP2POLB | |
| SCHEMBL31156495 | 0.59 | TSHR (0.51) | TSHRHPGDTP53USP2POLB | |
| SCHEMBL13423652 | 0.59 | GRM5 (0.36) | TSHRHPGDKMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |