Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.56 |
| ▸ | MAPK14 | Q16539 | 12/20 | 0.51 |
| ▸ | LCK | P06239 | 2/20 | 0.49 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | CSF1R | P07333 | 1/20 | 0.49 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1747651 | 0.89 | PDE4B (0.65) | PDE4BMAPK14 | |
| SCHEMBL1746553 | 0.88 | PDE4B (0.52) | PDE4BMAPK14 | |
| SCHEMBL1746258 | 0.82 | PDE4B (0.84) | PDE4BMAPK14 | |
| SCHEMBL1747376 | 0.73 | PDE4B (0.73) | PDE4B | |
| SCHEMBL1746589 | 0.72 | PDE4B (1.00) | PDE4B | |
| SCHEMBL1746610 | 0.71 | PDE4B (0.78) | PDE4B | |
| SCHEMBL1746288 | 0.70 | PDE4B (1.00) | PDE4B | |
| SCHEMBL1747621 | 0.70 | PDE4B (1.00) | PDE4B | |
| SCHEMBL31367847 | 0.70 | MAPK14 (0.74) | MAPK14LCKKDRCSF1RKIT | |
| SCHEMBL1746325 | 0.68 | PDE4B (0.73) | PDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |