Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12373174 | 1.00 | PARP1 (0.52) | PARP1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL1742200 | 1.00 | PARP1 (0.52) | PARP1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL2392874 | 0.86 | PARP1 (0.52) | PARP1ALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2392867 | 0.86 | PARP1 (0.52) | PARP1ALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL2392876 | 0.86 | PARP1 (0.52) | PARP1ALDH1A1MAPTSMN1; SMN2L3MBTL1 | |
| SCHEMBL4143293 | 0.84 | PARP1 (0.50) | PARP1ALDH1A1MAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL6786016 | 0.84 | PARP1 (0.50) | PARP1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4143287 | 0.84 | PARP1 (0.50) | PARP1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL4143291 | 0.84 | PARP1 (0.50) | PARP1ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL21119276 | 0.81 | PARP1 (0.47) | PARP1ALDH1A1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385940-B1 | 2,4,6-TRI-(HETEROARYLPHENYL)-PYRIDINES AND ELECTRON-TRANSPORTING MATERIALS COMPRISING THEM | GEN ELECTRIC (US) | 2015-10-28 | — | — | EP | disclosed |
| EP-2385941-B1 | ELECTRON-TRANSPORTING MATERIALS COMPRISING AND PROCESSES FOR MAKING THE SAME | GEN ELECTRIC (US) | 2014-03-26 | — | — | EP | disclosed |
| EP-2385941-A1 | ELECTRON-TRANSPORTING MATERIALS COMPRISING AND PROCESSES FOR MAKING THE SAME | General Electric Company (US) | 2011-11-16 | — | — | EP | disclosed |
| US-8039201-B2 | Antireflective coating composition and process thereof | AZ ELECTRONIC MATERIALS USA CORP. (US) | 2011-10-18 | — | — | US | disclosed |
| US-7989476-B2 | Electron-transporting materials and processes for making the same | GENERAL ELECTRIC COMPANY (US) | 2011-08-02 | — | — | US | disclosed |
| WO-2010080472-A1 | ELECTRON-TRANSPORTING MATERIALS COMPRISING AND PROCESSES FOR MAKING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2010-07-15 | — | — | WO | disclosed |
| US-20100171078-A1 | ELECTRON-TRANSPORTING MATERIALS AND PROCESSES FOR MAKING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2010-07-08 | — | — | US | disclosed |
| US-20100174086-A1 | ELECTRON-TRANSPORTING MATERIALS AND PROCESSES FOR MAKING THE SAME | GENERAL ELECTRIC COMPANY (US) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100174086-A1 | ELECTRON-TRANSPORTING MATERIALS AND PROCESSES FOR MAKING THE SAME | ABCB7, UQCRB, SLC13A3 | PARP1 1197/4885ALDH1A1 2975/4885MAPT 4216/4885 |
| US-20100171078-A1 | ELECTRON-TRANSPORTING MATERIALS AND PROCESSES FOR MAKING THE SAME | C3AR1, CRY1, C1S | PARP1 467/4885ALDH1A1 571/4885MAPT 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.