Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VDR | P11473 | 2/20 | 0.42 |
| ▸ | PPARD | Q03181 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745485 | 0.79 | FFAR1 (0.53) | VDRPPARDFFAR1BCHEFFAR4 | |
| SCHEMBL1746697 | 0.76 | PPARD (0.44) | VDRPPARDADRB2ADRB1FFAR1 | |
| SCHEMBL15679198 | 0.72 | FFAR1 (0.60) | VDRADRB2ADRB1FFAR1FFAR4 | |
| SCHEMBL1745058 | 0.72 | FFAR1 (0.61) | PPARDFFAR1FFAR4 | |
| SCHEMBL2003964 | 0.70 | ALDH1A1 (0.49) | VDRPPARDFFAR1FFAR4 | |
| SCHEMBL1587089 | 0.70 | EPHX2 (0.60) | VDRPPARDADRB2ADRB1FFAR1 | |
| SCHEMBL1745247 | 0.69 | FFAR1 (0.72) | FFAR1FFAR4 | |
| SCHEMBL1747136 | 0.69 | FFAR1 (0.72) | FFAR1FFAR4 | |
| SCHEMBL4518796 | 0.69 | KDM4E (0.58) | ADRB2ADRB1FFAR1FFAR4 | |
| SCHEMBL1745363 | 0.68 | FFAR1 (0.58) | VDRPPARDADRB2ADRB1FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2385032-A1 | GPR40 Receptor function regulator | Takeda Pharmaceutical Company Limited (JP) | 2011-11-09 | — | — | EP | disclosed |