Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.38 |
| ▸ | ACACB | O00763 | 8/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL862258 | 0.80 | — | — | |
| SCHEMBL13036241 | 0.80 | — | — | |
| SCHEMBL50404 | 0.80 | — | — | |
| SCHEMBL17640940 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MTNR1AMTNR1BACACB | |
| SCHEMBL8365133 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MTNR1AMTNR1BACACB | |
| SCHEMBL8150869 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MTNR1AMTNR1BACACB | |
| SCHEMBL10255628 | 0.77 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EMAPTTHRB | |
| SCHEMBL17057670 | 0.76 | ALDH1A1 (0.45) | ALDH1A1MTNR1AMTNR1BACACBSMN1; SMN2 | |
| SCHEMBL23259680 | 0.75 | PLA2G2C (0.39) | ALDH1A1 | |
| SCHEMBL20228713 | 0.75 | ALDH1A1 (0.37) | ALDH1A1MTNR1AMTNR1BACACBMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160022847-A1 | Radiotracer Compositions | GE HEALTHCARE LIMITED (GB) | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022847-A1 | Radiotracer Compositions | FOLR2, FOLR1, PAICS | ALDH1A1 29/4885MTNR1A 3677/4885MTNR1B 2681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.