Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.70 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.67 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.67 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.67 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.67 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.67 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.67 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.67 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.67 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.67 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.67 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.65 |
| ▸ | FAAH | O00519 | 5/20 | 0.62 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.61 |
| ▸ | BCHE | P06276 | 3/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | DRD4 | P21917 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9046417 | 0.92 | ACHE (0.60) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27558611 | 0.87 | CCR2 (0.62) | ACHECXCR4FAAHBCHE | |
| SCHEMBL17517685 | 0.86 | HDAC3 (0.68) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL429213 | 0.86 | ACHE (0.74) | ACHEBCHE | |
| SCHEMBL4592789 | 0.86 | HDAC3 (0.54) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL15478070 | 0.84 | ACHE (0.71) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14189662 | 0.84 | HDAC3 (0.72) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17515329 | 0.83 | HDAC3 (0.64) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL14681149 | 0.82 | ACHE (0.69) | ACHEHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12965729 | 0.82 | HDAC3 (0.62) | ACHEHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016012333-A1 | PESTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-01-28 | — | — | WO | disclosed |