Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17448166 | 0.86 | GBA1 (0.36) | GBA1 | |
| SCHEMBL13698582 | 0.79 | GBA1 (0.36) | GBA1 | |
| SCHEMBL17469458 | 0.78 | — | — | |
| SCHEMBL14772011 | 0.78 | GBA1 (0.35) | GBA1 | |
| SCHEMBL17449926 | 0.73 | — | — | |
| SCHEMBL22899135 | 0.72 | TNF (0.37) | GBA1 | |
| SCHEMBL14113880 | 0.70 | GBA1 (0.31) | GBA1 | |
| SCHEMBL23191952 | 0.66 | GBA1 (0.39) | GBA1 | |
| SCHEMBL19934858 | 0.66 | GBA1 (0.39) | GBA1 | |
| SCHEMBL13698581 | 0.66 | CA2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022914-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT OF OPHTHALMIC DISEASES AND CONDITIONS | MODERNA THERAPEUTICS, INC. (US) | 2016-02-11 | — | — | WO | disclosed |
| WO-2016014846-A1 | MODIFIED POLYNUCLEOTIDES FOR THE PRODUCTION OF INTRABODIES | MODERNA THERAPEUTICS, INC. (US) | 2016-01-28 | — | — | WO | disclosed |