Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13698582 | 0.82 | GBA1 (0.36) | GBA1CD209 | |
| SCHEMBL22899135 | 0.78 | TNF (0.37) | GBA1CD209 | |
| SCHEMBL17469459 | 0.78 | GBA1 (0.35) | GBA1 | |
| SCHEMBL12017368 | 0.73 | FBP1 (0.37) | — | |
| SCHEMBL23191952 | 0.72 | GBA1 (0.39) | GBA1CD209 | |
| SCHEMBL19934858 | 0.72 | GBA1 (0.39) | GBA1CD209 | |
| SCHEMBL24931089 | 0.71 | OGA (0.34) | — | |
| SCHEMBL14113880 | 0.70 | GBA1 (0.31) | GBA1 | |
| SCHEMBL12017367 | 0.69 | OGA (0.38) | — | |
| SCHEMBL19656077 | 0.68 | GBA1 (0.38) | GBA1CD209 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130065882-A1 | VLA-4 inhibitory drug | MACHINAGA NOBUO (JP) | 2013-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130065882-A1 | VLA-4 inhibitory drug | VCAM1, ITGB4, ITGA4 | GBA1 1458/4885CD209 184/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.