Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | PAM | P19021 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 3/20 | 0.48 |
| ▸ | CES1 | P23141 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1745930 | 1.00 | DGKA (0.55) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL1747417 | 1.00 | DGKA (0.55) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL1746020 | 1.00 | DGKA (0.55) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL1746182 | 1.00 | DGKA (0.55) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL1746036 | 1.00 | DGKA (0.55) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL1747165 | 1.00 | DGKA (0.55) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL5080872 | 0.86 | DGKA (0.53) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL5074853 | 0.86 | DGKA (0.53) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL5077124 | 0.86 | DGKA (0.53) | DGKALMNAPAMMAPTMAPK1 | |
| SCHEMBL6243474 | 0.83 | DGKA (0.55) | DGKALMNAPAMMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1948196-B1 | USE OF TETRAORGANOSILICON COMPOUNDS | SALAMA ZOSER B (DE) | 2012-12-26 | — | — | EP | claimed |
| EP-2563337-B1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | SALAMA ZOSER B (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2563337-B1 | CARRIER AND TARGETING SYSTEM COMPRISING A SIOSOMAL COMPOSITION FOR INTRACELLULAR DELIVERY AND TARGETING OF ACTIVE SUBSTANCE | SALAMA ZOSER B (DE) | 2017-07-26 | — | — | EP | disclosed |
| EP-2384743-A1 | Siosomal formulation for intracellular delivery and targeting of therapeutic agents | Salama, Zoser B. (DE) | 2011-11-09 | — | — | EP | disclosed |
| US-20100247578-A1 | CARRIER SYSTEM FOR BIOLOGICAL AGENTS CONTAINING ORGANOSILICON COMPOUNDS AND USES THEREOF | SALAMA ZOSER B | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100247578-A1 | CARRIER SYSTEM FOR BIOLOGICAL AGENTS CONTAINING ORGANOSILICON COMPOUNDS AND USES THEREOF | EXOSC5, EXOSC9, SSB | DGKA 3104/4885LMNA 1390/4885PAM 4229/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.