Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 1/20 | 0.47 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 12/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | F13A1 | P00488 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17470852 | 0.85 | POLB (0.38) | QPCTQPCTLMTNR1AMTNR1BKDM4E | |
| SCHEMBL19412585 | 0.79 | — | — | |
| SCHEMBL18381296 | 0.79 | TSHR (0.42) | MTNR1AMTNR1BLMNATSHRCYP2C19 | |
| SCHEMBL23019062 | 0.78 | CYP1A2 (0.44) | QPCTQPCTLKDM4ELMNACYP1A2 | |
| SCHEMBL27745562 | 0.76 | HTT (0.36) | KDM4EMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL22785768 | 0.76 | CYP3A4 (0.36) | HSD17B10CYP3A4 | |
| SCHEMBL17471006 | 0.75 | MTNR1A (0.53) | QPCTQPCTLMTNR1AMTNR1BBLM | |
| SCHEMBL4400656 | 0.75 | GABRR1 (0.53) | QPCTQPCTLMTNR1AMTNR1BKDM4E | |
| SCHEMBL20460450 | 0.74 | MEN1 (0.38) | KDM4ELMNAMEN1TSHRKMT2A | |
| SCHEMBL7073447 | 0.73 | HRH3 (0.41) | CYP1A2MEN1KMT2AHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9776996-B2 | Substituted 6,5-fused bicyclic heteroaryl compounds | Epizyme, Inc. (US) | 2017-10-03 | — | — | US | disclosed |
| US-20160024081-A1 | Substituted 6,5-Fused Bicyclic Heteroaryl Compounds | Epizyme, Inc. | 2016-01-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160024081-A1 | Substituted 6,5-Fused Bicyclic Heteroaryl Compounds | CYP3A5, PAICS, CYP4B1 | QPCT 229/4885QPCTL 2009/4885MTNR1A 2478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.