Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 15/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 15/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 12/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 11/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21181331 | 0.82 | BTK (0.44) | CYP1A2CYP3A4HSD17B10TSHRALDH1A1 | |
| SCHEMBL18176950 | 0.82 | BCHE (0.44) | TDP1 | |
| SCHEMBL30919984 | 0.79 | L3MBTL1 (0.45) | CYP3A4ALDH1A1LMNAKDM4EMAPK1 | |
| SCHEMBL17234487 | 0.79 | L3MBTL1 (0.45) | CYP3A4ALDH1A1LMNAKDM4EMAPK1 | |
| SCHEMBL7668696 | 0.79 | CYP3A4 (0.59) | CYP1A2CYP3A4TSHRCYP2C9LMNA | |
| SCHEMBL8826207 | 0.79 | HTT (0.59) | CYP1A2CYP3A4HSD17B10ALOX15ALDH1A1 | |
| SCHEMBL536914 | 0.79 | BRAF (0.47) | CYP1A2HSD17B10TSHRHIF1A | |
| SCHEMBL30479201 | 0.79 | HTT (0.59) | CYP1A2CYP3A4HSD17B10ALOX15ALDH1A1 | |
| SCHEMBL17471007 | 0.78 | QPCT (0.47) | CYP1A2CYP3A4HSD17B10TSHRALDH1A1 | |
| SCHEMBL17009419 | 0.78 | SMN1; SMN2 (0.36) | CYP1A2TSHRALOX15LMNACLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3783105-A1 | SECRETORY IMMUNOGLOBULIN A (SIGA)-BINDING NUCLEIC ACID MOLECULE, SENSOR FOR SIGA ANALYSIS, AND ANALYSIS METHOD FOR SIGA | NEC Solution Innovators, Ltd. (JP) | 2021-02-24 | — | — | EP | disclosed |