Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30499569 | 0.79 | APP (0.54) | ALDH1A1MEN1KMT2AELANESRC | |
| SCHEMBL20413677 | 0.79 | L3MBTL1 (0.56) | KDM4EALDH1A1TSHRCYP2C19MEN1 | |
| SCHEMBL3158083 | 0.79 | KDM4E (0.47) | KDM4EALDH1A1TSHRCYP2C19ELANE | |
| SCHEMBL9983699 | 0.77 | ALDH1A1 (0.60) | KDM4EEGFRALDH1A1TSHRCYP2C19 | |
| SCHEMBL14006038 | 0.76 | ALDH1A1 (0.51) | KDM4EALDH1A1TSHRCYP2C19CCNA2 | |
| SCHEMBL9876637 | 0.75 | PTGER1 (0.50) | KDM4EEGFRALDH1A1TSHRCYP2C19 | |
| SCHEMBL29224069 | 0.74 | ELANE (0.50) | KDM4EALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL1747623 | 0.74 | GSK3B (0.54) | EGFRALDH1A1MEN1PI4KAKMT2A | |
| SCHEMBL10831975 | 0.74 | MAPT (0.47) | KDM4EEGFRALDH1A1TSHRCYP2C19 | |
| SCHEMBL4753475 | 0.73 | EGFR (0.49) | KDM4EEGFRALDH1A1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| EP-2380890-A1 | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors | Almirall, S.A. (ES) | 2011-10-26 | — | — | EP | disclosed |
| US-20110253549-A1 | WASHING APPARATUS AND METHOD OF DEODORIZING WASHING WATER | KANNO MINORU | 2011-10-20 | — | — | US | disclosed |